Literature DB >> 15104518

Phorbasterones A-D, cytotoxic nor-ring A steroids from the sponge Phorbas amaranthus.

Makoto N Masuno1, Joseph R Pawlik, Tadeusz F Molinski.   

Abstract

The sponge Phorbas amaranthus from Florida contains the new ring A-contracted steroids, phorbasterones A-D, and the known anthosterones A and B. The structures of phorbasterones A-D were determined by interpretation of their spectroscopic data. Phorbasterones show moderate cytotoxicity against HCT-116 tumor cells.

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Year:  2004        PMID： 15104518     DOI： 10.1021/np034037j

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  5 in total

1.  Amaranzoles B-F, imidazole-2-carboxy steroids from the marine sponge Phorbas amaranthus. C24-N- and C24-O-analogues from a divergent oxidative biosynthesis.

Authors:  Brandon I Morinaka; Joseph R Pawlik; Tadeusz F Molinski
Journal:  J Org Chem       Date:  2010-04-16       Impact factor: 4.354

2.  Red Algae (Rhodophyta) from the Coast of Madagascar: Preliminary Bioactivity Studies and Isolation of Natural Products.

Authors:  Marie Pascaline Rahelivao; Margit Gruner; Hanta Andriamanantoanina; Bakolinirina Andriamihaja; Ingmar Bauer; Hans-Joachim Knölker
Journal:  Mar Drugs       Date:  2015-07-07       Impact factor: 5.118

3.  Crellasterones A and B: A-Norsterol Derivatives from the New Caledonian Sponge Crella incrustans.

Authors:  Kavita Ragini; Andrew M Piggott; Peter Karuso
Journal:  Mar Drugs       Date:  2017-06-15       Impact factor: 5.118

Review 4.  Bioactive natural products from marine sponges belonging to family Hymedesmiidae.

Authors:  Asmaa Abo Elgoud Said; Basma Khalaf Mahmoud; Eman Zekry Attia; Usama Ramadan Abdelmohsen; Mostafa Ahmed Fouad
Journal:  RSC Adv       Date:  2021-04-30       Impact factor: 3.361

Review 5.  Exploring Chemical Diversity of Phorbas Sponges as a Source of Novel Lead Compounds in Drug Discovery.

Authors:  Alessia Caso; Fernanda Barbosa da Silva; Germana Esposito; Roberta Teta; Gerardo Della Sala; Laura P A Nunes Cavalcanti; Alessandra Leda Valverde; Roberto Carlos C Martins; Valeria Costantino
Journal:  Mar Drugs       Date:  2021-11-26       Impact factor: 5.118
  5 in total

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