Literature DB >> 15104434

1-(Alkyl/arylthiocarbamoyl)benzotriazoles as stable isothiocyanate equivalents: synthesis of Di- and trisubstituted thioureas.

Alan R Katritzky1, Stephane Ledoux, Rachel M Witek, Satheesh K Nair.   

Abstract

1-(Alkyl/arylthiocarbamoyl)benzotriazoles 4a-i were synthesized in yields of 91-99% from bis(benzotriazolyl)methanethione (3). Reagents 4a-g were then used as isothiocyanate equivalents for the efficient synthesis of 10 secondary and 14 tertiary thioureas in high-yielding, convenient processes.

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Year:  2004        PMID: 15104434     DOI: 10.1021/jo035680d

Source DB:  PubMed          Journal:  J Org Chem        ISSN: 0022-3263            Impact factor:   4.354


  5 in total

1.  One-step construction of unsymmetrical thioureas and oxazolidinethiones from amines and carbon disulfide via a cascade reaction sequence.

Authors:  Chaochao Ding; Shaoli Wang; Yaoguang Sheng; Qian Dai; Yunjie Zhao; Guang Liang; Zengqiang Song
Journal:  RSC Adv       Date:  2019-08-27       Impact factor: 4.036

Review 2.  Mechanochemistry as an emerging tool for molecular synthesis: what can it offer?

Authors:  Joseph L Howard; Qun Cao; Duncan L Browne
Journal:  Chem Sci       Date:  2018-03-07       Impact factor: 9.825

3.  Synthesis of New Steroidal Carbamates with Plant-Growth-Promoting Activity: Theoretical and Experimental Evidence.

Authors:  Daylin Fernández Pacheco; Leonardo González Ceballos; Armando Zaldo Castro; Marcos R Conde González; Laura González de la Torre; Lia Pérez Rostgaard; Luis Espinoza; Katy Díaz; Andrés F Olea; Yamilet Coll García
Journal:  Int J Mol Sci       Date:  2021-02-26       Impact factor: 5.923

Review 4.  Mechanochemical synthesis of thioureas, ureas and guanidines.

Authors:  Vjekoslav Štrukil
Journal:  Beilstein J Org Chem       Date:  2017-09-01       Impact factor: 2.883

Review 5.  Chiral Thioureas-Preparation and Significance in Asymmetric Synthesis and Medicinal Chemistry.

Authors:  Franz Steppeler; Dominika Iwan; Elżbieta Wojaczyńska; Jacek Wojaczyński
Journal:  Molecules       Date:  2020-01-18       Impact factor: 4.411

  5 in total

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