Literature DB >> 15103420

[Fetal wound healing: current status and new perspectives].

E A Huhn1, C Jannowitz, H Boos, M A Papadopulos, H F Zeilhofer, J Henke, D Müller, L Kovacs, E Biemer, N A Papadopulos.   

Abstract

The characteristic of fetal wound healing is scarless wound repair in early gestation. During the last two decades, intensive research efforts have focused on unraveling the molecular regulations underlying the phenomenon of scarless wound healing. Better understanding of synthesis and degradation will enable us to develop important therapeutic options for the prevention and reduction of scarring. The aim of this article is to present an overview, discuss the most important research works of the last two decades on the field of fetal wound healing, and report current therapeutic developments for the modulation of adult wound repair. Recent experimental results using these new therapeutic approaches are very promising and present great possibilities and chances for future surgery.

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Year:  2004        PMID: 15103420     DOI: 10.1007/s00104-004-0878-9

Source DB:  PubMed          Journal:  Chirurg        ISSN: 0009-4722            Impact factor:   0.955


  77 in total

1.  Decreased expression of fibroblast and keratinocyte growth factor isoforms and receptors during scarless repair.

Authors:  Catherine M Dang; Steven R Beanes; Chia Soo; Kang Ting; Prosper Benhaim; Marc H Hedrick; H Peter Lorenz
Journal:  Plast Reconstr Surg       Date:  2003-05       Impact factor: 4.730

Review 2.  Tooth morphogenesis and cell differentiation.

Authors:  I Thesleff; P Nieminen
Journal:  Curr Opin Cell Biol       Date:  1996-12       Impact factor: 8.382

Review 3.  [Pathology of wound healing].

Authors:  F Hofstädter
Journal:  Chirurg       Date:  1995-03       Impact factor: 0.955

4.  Bone morphogenetic protein-2 induces scar formation and skin maturation in the second trimester fetus.

Authors:  E J Stelnicki; M T Longaker; D Holmes; K Vanderwall; M R Harrison; C Largman; W Y Hoffman
Journal:  Plast Reconstr Surg       Date:  1998-01       Impact factor: 4.730

5.  Tissue repair in the fetal intestinal tract occurs with adhesions, fibrosis, and neovascularization.

Authors:  B A Mast; C T Albanese; S Kapadia
Journal:  Ann Plast Surg       Date:  1998-08       Impact factor: 1.539

6.  Amniotic fluid fibronectin concentrations with advancing gestational age.

Authors:  M C Harris; M T Mennuti; J A Kline; R A Polin
Journal:  Obstet Gynecol       Date:  1988-10       Impact factor: 7.661

7.  Transcriptional regulation of the rat vascular endothelial growth factor gene by hypoxia.

Authors:  A P Levy; N S Levy; S Wegner; M A Goldberg
Journal:  J Biol Chem       Date:  1995-06-02       Impact factor: 5.157

8.  Ontogeny of fetal sheep polymorphonuclear leukocyte phagocytosis.

Authors:  R W Jennings; N S Adzick; M T Longaker; B W Duncan; H Scheuenstuhl; T K Hunt
Journal:  J Pediatr Surg       Date:  1991-07       Impact factor: 2.545

Review 9.  Growth factors and wound healing: biochemical properties of growth factors and their receptors.

Authors:  N T Bennett; G S Schultz
Journal:  Am J Surg       Date:  1993-06       Impact factor: 2.565

10.  Biology of fetal wound healing: hyaluronate receptor expression in fetal fibroblasts.

Authors:  S M Alaish; D Yager; R F Diegelmann; I K Cohen
Journal:  J Pediatr Surg       Date:  1994-08       Impact factor: 2.545

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  1 in total

1.  Local administration of TGF-beta1 to reinforce the anterior abdominal wall in a rat model of incisional hernia.

Authors:  M Korenkov; N Yuecel; J Koebke; J Schierholz; Ch Morsczeck; I Tasci; E A M Neugebauer; M Nagelschmidt
Journal:  Hernia       Date:  2005-05-24       Impact factor: 4.739

  1 in total

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