| Literature DB >> 15102820 |
Latifu A Sanni1, William Jarra, Ching Li, Jean Langhorne.
Abstract
During a Plasmodium chabaudi infection in interleukin-10 (IL-10) knockout mice, there is greater parasite sequestration, more severe cerebral edema, and a high frequency of cerebral hemorrhage compared with infection of C57BL/6 mice. Anti-tumor necrosis factor alpha treatment ameliorated both cerebral edema and hemorrhages, suggesting that proinflammatory responses contributed to cerebral complications in infected IL-10(-/-) mice.Entities:
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Year: 2004 PMID: 15102820 PMCID: PMC387911 DOI: 10.1128/IAI.72.5.3054-3058.2004
Source DB: PubMed Journal: Infect Immun ISSN: 0019-9567 Impact factor: 3.441