Literature DB >> 15100519

Should patients over 85 years old be operated on for colorectal cancer?

Kunio Takeuchi1, Yasushi Tsuzuki, Tetsu Ando, Masao Sekihara, Takashi Hara, Takayuki Kori, Hiroki Nakajima, Takayuki Asao, Hiroyuki Kuwano.   

Abstract

BACKGROUND: The aim of this study is to evaluate risk factors for mortality, morbidity, and long-term survival in very old patients with colorectal cancer compared with old patients.
METHODS: Patients operated on with colorectal cancer aged 75 years old or older were divided into 2 groups: Group A (75-84 years, n = 93) and Group B (>or=85, n = 21).
RESULTS: The serum albumin level, oxygen pressure in arterial blood gases, and forced expiratory volume in 1 second in Group B were significantly lower than in Group A, respectively (P = 0.0094, 0.0264, 0.0363). Pulmonary complications were developed significantly more frequently in Group B than in Group A (P = 0.0019). Group B had a significantly higher mortality rate than Group A (P = 0.0477). There was no significant difference between the 2 groups in the 2- and 5-year survival rates.
CONCLUSIONS: Very old patients with colorectal cancer should not be denied surgery on account of chronological age alone, although the perioperative risks for the very old are very high.

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Mesh:

Year:  2004        PMID: 15100519     DOI: 10.1097/00004836-200405000-00004

Source DB:  PubMed          Journal:  J Clin Gastroenterol        ISSN: 0192-0790            Impact factor:   3.062


  6 in total

1.  Complications and risk prediction in treatment of elderly patients with rectal cancer.

Authors:  T Stornes; A Wibe; B H Endreseth
Journal:  Int J Colorectal Dis       Date:  2015-08-23       Impact factor: 2.571

2.  Surgery for Colorectal Cancer in Elderly Patients: How Could We Improve Early Outcomes ?

Authors:  Mahdi Bouassida; Hédi Charrada; Mohamed Fadhel Chtourou; Lamine Hamzaoui; Mohamed Mongi Mighri; Selim Sassi; Mohamed M'Saddak Azzouz; Hassen Touinsi
Journal:  J Clin Diagn Res       Date:  2015-05-01

3.  Impact of age-related comorbidity on results of colorectal cancer surgery.

Authors:  Corrado Pedrazzani; Guido Cerullo; Giovanni De Marco; Daniele Marrelli; Alessandro Neri; Alfonso De Stefano; Enrico Pinto; Franco Roviello
Journal:  World J Gastroenterol       Date:  2009-12-07       Impact factor: 5.742

4.  Outcome of surgical treatment of colorectal cancer in the elderly.

Authors:  Andrea Fontani; Jacopo Martellucci; Serenella Civitelli; Gabriello Tanzini
Journal:  Updates Surg       Date:  2011-06-10

5.  Surgical treatment of colorectal cancer in patients aged over 80 years.

Authors:  Jyrki T Mäkelä; Heikki Kiviniemi
Journal:  Int J Colorectal Dis       Date:  2012-02-11       Impact factor: 2.571

6.  Clinico-Pathological Caracteristics, Therapeutic Features and Post-operative Course of Colorectal Cancer in Elderly Patients.

Authors:  Mahdi Bouassida; Mohamed Fadhel Chtourou; Lamine Hamzaoui; Selim Sassi; Mohamed Mongi Mighri; Mohamed M'saddak Azzouz; Hassen Touinsi; Sadok Sassi
Journal:  J Clin Diagn Res       Date:  2014-01-12
  6 in total

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