| Literature DB >> 15097962 |
Hatem M El-Gamal1, Leslie Robinson-Bostom, Kirk D Saddler, Teddy Pan, Martin C Mihm.
Abstract
Two cases of compound melanocytic nevi with granular cell changes were studied. Histological examination revealed compound melanocytic nevi with a portion of the dermal component exhibiting a sheet like proliferation of nevoid cells with granular cytoplasm. Immunohistochemically, both populations of cells stained positive for S-100 and Melan-A. However, HMB-45 was positive only for the nevus cells with granular cytoplasm. We believe this represents granular cytoplasmic changes of nevus cells and does not denote malignant transformation.Entities:
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Year: 2004 PMID： 15097962 DOI： 10.1016/j.jaad.2003.11.068
Source DB: PubMed Journal: J Am Acad Dermatol ISSN： 0190-9622 Impact factor: 11.527