Literature DB >> 15097933

Acute development of multiple keratoacanthomas and squamous cell carcinomas after treatment with infliximab.

Adam C Esser1, Andy Abril, Scott Fayne, John A Doyle.   

Abstract

Infliximab, a chimeric mouse-human monoclonal antibody, blocks the action of tumor necrosis factor-alpha and is a highly effective treatment for several inflammatory disorders, including inflammatory bowel disease and rheumatoid arthritis. Although safety data are encouraging, immunosuppressive sequelae may result. We report the acute development of multiple squamous cell carcinomas and keratoacanthomas in a patient receiving infliximab for rheumatoid arthritis.

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Year:  2004        PMID: 15097933     DOI: 10.1016/j.jaad.2003.11.044

Source DB:  PubMed          Journal:  J Am Acad Dermatol        ISSN: 0190-9622            Impact factor:   11.527


  15 in total

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4.  Hepatocellular carcinoma occurring in a patient with Crohn's disease treated with both azathioprine and infliximab.

Authors:  Shawn C Chen; Oscar W Cummings; Michael P Hartley; Carol A Filomena; Won Kyoo Cho
Journal:  Dig Dis Sci       Date:  2006-05-03       Impact factor: 3.199

5.  Effects of infliximab on sister chromatid exchanges and chromosomal aberration in patients with rheumatoid arthritis.

Authors:  M Atteritano; S Mazzaferro; S Mantuano; G L Bagnato; G F Bagnato
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Review 9.  Development of primary malignant melanoma during treatment with a TNF-α antagonist for severe Crohn's disease: a case report and review of the hypothetical association between TNF-α blockers and cancer.

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10.  The influence of anti-TNF therapy upon incidence of keratinocyte skin cancer in patients with rheumatoid arthritis: longitudinal results from the British Society for Rheumatology Biologics Register.

Authors:  Louise K Mercer; Adele C Green; James B Galloway; Rebecca Davies; Mark Lunt; William G Dixon; Kath D Watson; Deborah P M Symmons; Kimme L Hyrich
Journal:  Ann Rheum Dis       Date:  2012-01-12       Impact factor: 19.103

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