Literature DB >> 15096596

Is 11beta-hydroxysteroid dehydrogenase type 1 a good therapeutic target for blockade of glucocorticoid actions?

George P Chrousos1.   

Abstract

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Year:  2004        PMID： 15096596      PMCID： PMC404042          DOI： 10.1073/pnas.0401671101

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


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2.  Responses of plasma adrenocorticotropin, cortisol, and dehydroepiandrosterone to ovine corticotropin-releasing hormone in healthy aging men.

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3.  Effect of chronic treatment with the glucocorticoid antagonist RU 486 in man: toxicity, immunological, and hormonal aspects.

Authors:  L Laue; M T Lotze; G P Chrousos; K Barnes; D L Loriaux; T A Fleisher
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4.  Apparent cortisone reductase deficiency: a functional defect in 11beta-hydroxysteroid dehydrogenase type 1.

Authors:  A Jamieson; A M Wallace; R Andrew; B S Nunez; B R Walker; R Fraser; P C White; J M Connell
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Review 5.  Organization of the stress system and its dysregulation in melancholic and atypical depression: high vs low CRH/NE states.

Authors:  P W Gold; G P Chrousos
Journal:  Mol Psychiatry       Date:  2002       Impact factor: 15.992

6.  11Beta-hydroxysteroid dehydrogenase inhibition improves cognitive function in healthy elderly men and type 2 diabetics.

Authors:  Thekkepat C Sandeep; Joyce L W Yau; Alasdair M J MacLullich; June Noble; Ian J Deary; Brian R Walker; Jonathan R Seckl
Journal:  Proc Natl Acad Sci U S A       Date:  2004-04-07       Impact factor: 11.205

7.  Impaired nighttime sleep in healthy old versus young adults is associated with elevated plasma interleukin-6 and cortisol levels: physiologic and therapeutic implications.

Authors:  Alexandros N Vgontzas; Manolis Zoumakis; Edward O Bixler; Hung-Mo Lin; Paolo Prolo; Antonio Vela-Bueno; Anthony Kales; George P Chrousos
Journal:  J Clin Endocrinol Metab       Date:  2003-05       Impact factor: 5.958

Review 8.  Tissue glucocorticoid resistance/hypersensitivity syndromes.

Authors:  Tomoshige Kino; Massimo U De Martino; Evangelia Charmandari; Marco Mirani; George P Chrousos
Journal:  J Steroid Biochem Mol Biol       Date:  2003-06       Impact factor: 4.292

Review 9.  Endocrine withdrawal syndromes.

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Journal:  Endocr Rev       Date:  2003-08       Impact factor: 19.871
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5.  Effects of selective and non-selective glucocorticoid receptor II antagonists on rapid-onset diabetes in young rats.

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6.  A review of the serotonin transporter and prenatal cortisol in the development of autism spectrum disorders.

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7.  A novel 11β-hydroxysteroid dehydrogenase type1 inhibitor CNX-010-49 improves hyperglycemia, lipid profile and reduces body weight in diet induced obese C57B6/J mice with a potential to provide cardio protective benefits.

Authors:  Tharappel M Anil; Anilkumar Dandu; KrishnaReddy Harsha; Jaideep Singh; Nitya Shree; Venkatesh Satish Kumar; Mudigere N Lakshmi; Venkategowda Sunil; Chandrashekaran Harish; Gundalmandikal V Balamurali; Baisani S Naveen Kumar; Aralakuppe S Gopala; Shivakumar Pratibha; ManojKumar Sadasivuni; Mammen O Anup; Yoganand Moolemath; Marikunte V Venkataranganna; Madanahalli R Jagannath; Baggavalli P Somesh
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  7 in total

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