Literature DB >> 1509495

Fate of a single dose of the 14C-labelled mycotoxin, fumonisin B1, in rats.

G S Shephard1, P G Thiel, E W Sydenham, J F Alberts, W C Gelderblom.   

Abstract

The fate of the mycotoxin, fumonisin B1, (FB1) dosed to rats by i.p. injection and by gavage was traced using 14C-labelled FB1. Twenty-four hours after i.p. injection, 66% of the radioactivity was recovered in faeces, 32% in urine, 1% in liver and trace amounts (less than 1%) in kidney and red blood cells. When dosed by gavage, all (101%) radioactivity was recovered in faeces and trace amounts were found in urine, liver, kidney and red blood cells. The bulk of the radioactivity recovered was unmetabolized FB1.

Entities:  

Mesh:

Substances:

Year:  1992        PMID: 1509495     DOI: 10.1016/0041-0101(92)90011-s

Source DB:  PubMed          Journal:  Toxicon        ISSN: 0041-0101            Impact factor:   3.033


  9 in total

1.  Evalution of liquid media for fumonisin production byFusarium moniliforme MCR 826.

Authors:  J F Alberts; W C Gelderblom; W F Marasas; J P Rheeder
Journal:  Mycotoxin Res       Date:  1994-09       Impact factor: 3.833

2.  Effect ofin vitro digestion on fumonisin B1 in corn flakes.

Authors:  E L Motta; P M Scott
Journal:  Mycotoxin Res       Date:  2007-12       Impact factor: 3.833

3.  Fumonisin B1 metabolism by bovine liver microsomes.

Authors:  M Spotti; G Pompa; F Caloni
Journal:  Vet Res Commun       Date:  2001-08       Impact factor: 2.459

4.  In vivo effects of fumonisin B1-producing and fumonisin B1-nonproducing Fusarium moniliforme isolates are similar: fumonisins B2 and B3 cause hepato- and nephrotoxicity in rats.

Authors:  K A Voss; R D Plattner; R T Riley; F I Meredith; W P Norred
Journal:  Mycopathologia       Date:  1998       Impact factor: 2.574

5.  Production of [14C]fumonisin B1 by Fusarium moniliforme MRC 826 in corn cultures.

Authors:  J F Alberts; W C Gelderblom; R Vleggaar; W F Marasas; J P Rheeder
Journal:  Appl Environ Microbiol       Date:  1993-08       Impact factor: 4.792

Review 6.  Fumonisin toxicosis in swine: an overview of porcine pulmonary edema and current perspectives.

Authors:  W M Haschek; L A Gumprecht; G Smith; M E Tumbleson; P D Constable
Journal:  Environ Health Perspect       Date:  2001-05       Impact factor: 9.031

Review 7.  An overview of rodent toxicities: liver and kidney effects of fumonisins and Fusarium moniliforme.

Authors:  K A Voss; R T Riley; W P Norred; C W Bacon; F I Meredith; P C Howard; R D Plattner; T F Collins; D K Hansen; J K Porter
Journal:  Environ Health Perspect       Date:  2001-05       Impact factor: 9.031

Review 8.  Developmental Toxicity of Mycotoxin Fumonisin B₁ in Animal Embryogenesis: An Overview.

Authors:  Chompunut Lumsangkul; Hsin-I Chiang; Neng-Wen Lo; Yang-Kwang Fan; Jyh-Cherng Ju
Journal:  Toxins (Basel)       Date:  2019-02-13       Impact factor: 4.546

Review 9.  Development and Limitations of Exposure Biomarkers to Dietary Contaminants Mycotoxins.

Authors:  Paul C Turner; Jessica A Snyder
Journal:  Toxins (Basel)       Date:  2021-04-28       Impact factor: 4.546

  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.