Literature DB >> 15094448

The role of 99mTc mebrofenin hepatobiliary scanning in predicting common bile duct stones in patients with gallstone disease.

Mohammed Iqbal1, Sandeep Aggarwal, Rakesh Kumar, Pramod Kumar Garg, Suman Bandhu, Arvind Kumar, Rajinder Parshad, Sandeep Guleria.   

Abstract

BACKGROUND: A dilated common bile duct and/or elevated serum alkaline phosphatase, raises a suspicion of bile duct stone(s) in patients with gallstones. Cholangiography, either endoscopic retrograde cholangiopancreatography (ERCP) or magnetic resonance cholangiopancreatography (MRCP), is the best method for diagnosing bile duct stones. ERCP has the disadvantage of being invasive, and there is a risk of complications; while MRCP is costly and is not widely available. AIM: The objective of the present study was to evaluate the role of hepatobiliary nuclear scanning in diagnosing bile duct stones.
METHODS: Twenty-five patients with suspected common bile duct (CBD) stones underwent hepatobiliary scintigraphy. The results of scintigraphy were compared with cholangiograms obtained by ERCP in 11 patients and MRCP in 14 patients, considering MRCP/ERCP as the 'gold standard'.
RESULTS: Scintigraphy showed features suggestive of CBD stones in 11 of the 25 patients. The results of ERCP/MRCP confirmed that eight of them had stones. Scintigraphy showed no features of CBD stones in the remaining 14 patients. ERCP/MRCP showed CBD stones in two of these 14 patients. Thus, scintigraphy had a sensitivity of 80% and a specificity of 80%.
CONCLUSION: We conclude that scintigraphy has good sensitivity and specificity in predicting CBD stones in patients with gallstone disease and a dilated CBD.

Entities:  

Mesh:

Substances:

Year:  2004        PMID: 15094448     DOI: 10.1097/00006231-200403000-00012

Source DB:  PubMed          Journal:  Nucl Med Commun        ISSN: 0143-3636            Impact factor:   1.690


  1 in total

1.  Predictor of abnormal gallbladder ejection fraction in patients with atypical biliary pain: Histopathological point of view.

Authors:  Jun Uk Lim; Kwang Ro Joo; Kyu Yeoun Won; Sung-Jig Lim; Sun-Hyung Joo; You-Jung Yang
Journal:  Medicine (Baltimore)       Date:  2017-12       Impact factor: 1.817

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.