A silent epidemic of environmental metal poisoning?

The main objective of this paper is to provoke and stimulate debate on the health effects of long-term, low-level exposure of human populations to toxic metals. Over one billion (10(9)) human guinea pigs are now being exposed to elevated levels of toxic metals and metalloids in the environment. The number of persons suffering from subclinical metal poisoning is believed to be several million. A large portion of the cases are in developed countries but the urban areas of developing countries have become 'hot-spots' of metal pollution, and the populations of such countries are particularly susceptible to environmental toxins. As a global problem, the potential health effects of metallic hazards should be a matter of public health concern, especially if the emissions of toxic metals into the environment continue at the current rate.