Literature DB >> 15091848

Detection of a carcinogen, 2-amino-1-methyl-6-phenylimidazo [4,5-b]pyridine, in airborne particles and diesel-exhaust particles.

S Manabe1, N Kurihara, O Wada, S Izumikawa, K Asakuno, M Morita.   

Abstract

A carcinogen, 2-amino-1-methyl-6-phenylimidazo [4,5-b]-pyridine (PhIP), has been measured in airborne particles, diesel-exhaust particles, and incineration ash from garbage-burning plants. PhIP was found in all kinds of samples. In the light of the present results, together with the previous findings that PhIP was present in cooked foods and cigarette smoke, PhIP is likely to be an ubiquitous environmental pollutant. These observations also suggest that PhIP may be formed through the combustion process.

Entities:  

Year:  1993        PMID: 15091848     DOI: 10.1016/0269-7491(93)90049-t

Source DB:  PubMed          Journal:  Environ Pollut        ISSN: 0269-7491            Impact factor:   8.071


  16 in total

1.  DNA adducts of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and 4-aminobiphenyl are infrequently detected in human mammary tissue by liquid chromatography/tandem mass spectrometry.

Authors:  Dan Gu; Robert J Turesky; Yeqing Tao; Sophie A Langouët; Gwendoline C Nauwelaërs; Jian-Min Yuan; Douglas Yee; Mimi C Yu
Journal:  Carcinogenesis       Date:  2011-11-09       Impact factor: 4.944

2.  Identification of carcinogen DNA adducts in human saliva by linear quadrupole ion trap/multistage tandem mass spectrometry.

Authors:  Erin E Bessette; Simon D Spivack; Angela K Goodenough; Tao Wang; Shailesh Pinto; Fred F Kadlubar; Robert J Turesky
Journal:  Chem Res Toxicol       Date:  2010-07-19       Impact factor: 3.739

3.  Metabolism of the Tobacco Carcinogen 2-Amino-9H-pyrido[2,3-b]indole (AαC) in Primary Human Hepatocytes.

Authors:  Medjda Bellamri; Ludovic Le Hegarat; Robert J Turesky; Sophie Langouët
Journal:  Chem Res Toxicol       Date:  2016-12-15       Impact factor: 3.739

4.  Mouse lung CYP1A1 catalyzes the metabolic activation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).

Authors:  Xiaochao Ma; Jeffrey R Idle; Michael A Malfatti; Kristopher W Krausz; Daniel W Nebert; Chong-Sheng Chen; James S Felton; David J Waxman; Frank J Gonzalez
Journal:  Carcinogenesis       Date:  2006-10-19       Impact factor: 4.944

5.  Towards a Field-Portable Real-Time Organic and Elemental Carbon Monitor.

Authors:  D A Parks; K V Raj; C A Berry; A T Weakley; P R Griffiths; A L Miller
Journal:  Min Metall Explor       Date:  2019-04-22

Review 6.  Metabolism and biomarkers of heterocyclic aromatic amines in molecular epidemiology studies: lessons learned from aromatic amines.

Authors:  Robert J Turesky; Loic Le Marchand
Journal:  Chem Res Toxicol       Date:  2011-06-20       Impact factor: 3.739

7.  Effect of N-acetyltransferase 2 polymorphism on tumor target tissue DNA adduct levels in rapid and slow acetylator congenic rats administered 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine or 2-amino-3,8-dimethylimidazo-[4,5-f]quinoxaline.

Authors:  Kristin J Metry; Jason R Neale; Jean Bendaly; Ned B Smith; William M Pierce; David W Hein
Journal:  Drug Metab Dispos       Date:  2009-08-10       Impact factor: 3.922

8.  DNA adduct formation of 4-aminobiphenyl and heterocyclic aromatic amines in human hepatocytes.

Authors:  Gwendoline Nauwelaers; Erin E Bessette; Dan Gu; Yijin Tang; Julie Rageul; Valérie Fessard; Jian-Min Yuan; Mimi C Yu; Sophie Langouët; Robert J Turesky
Journal:  Chem Res Toxicol       Date:  2011-04-19       Impact factor: 3.739

9.  Detection of 2-amino-1-methyl-6-phenylimidazo [4,5-b]-pyridine (PhIP)-DNA adducts in human pancreatic tissues.

Authors:  J Zhu; A Rashid; K Cleary; J L Abbruzzese; H Friess; S Takahashi; T Shirai; D Li
Journal:  Biomarkers       Date:  2006 Jul-Aug       Impact factor: 2.658

10.  Measurement of the Heterocyclic Amines 2-Amino-9H-pyrido[2,3-b]indole and 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in Urine: Effects of Cigarette Smoking.

Authors:  Dmitri Konorev; Joseph S Koopmeiners; Yijin Tang; Elizabeth A Franck Thompson; Joni A Jensen; Dorothy K Hatsukami; Robert J Turesky
Journal:  Chem Res Toxicol       Date:  2015-12-03       Impact factor: 3.739

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