Literature DB >> 15091209

Safety of modified radical neck dissection for differentiated thyroid carcinoma.

Michael E Kupferman1, D Michael Patterson, Susan J Mandel, Virginia LiVolsi, Randal S Weber.   

Abstract

OBJECTIVES/HYPOTHESIS: The management of cervical metastases from differentiated thyroid carcinoma (DTC) remains controversial. Most surgeons perform a neck dissection (ND) for clinically apparent disease. The extent of nodal dissection varies from regional to comprehensive. Morbidity from ND in the setting of DTC remains high, particularly when performed in the setting of a thyroidectomy (TT). To determine complications from ND for DTC, we retrospectively reviewed our surgical experience of modified radical neck dissection for nodal metastases. STUDY
DESIGN: Retrospective chart review.
METHODS: Between 1997 and 2002, 39 consecutive patients (31 females and 8 males) underwent 44 comprehensive NDs of levels II-V for DTC. Central compartment dissection (CCD) (levels VI and VII) was also performed during 23 of these procedures. Twenty (45.5%) patients had prior treatment elsewhere. Preoperative pathology revealed papillary carcinoma in 22 patients (56.4%), tall cell variant in 11 (28.2%), and follicular variant in 6 (15.4%).
RESULTS: Ten patients (20%) underwent ND alone, whereas 6 (14%) underwent simultaneous ND and TT. Fifteen patients underwent simultaneous ND, TT, and CCD (30%). Temporary hypocalcemia occurred after 21% of NDs that were performed in the setting of either TT or CCD or both. There were no cases of permanent hypoparathyroidism. Transient regional lymph node (RLN) paresis occurred in two patients and was associated with a concomitant central compartment nodal dissection; there were no permanent RLN palsies. Transient spinal accessory nerve paresis developed after 27% of NDs performed. Two patients developed chyle leaks.
CONCLUSIONS: When ND is necessary for the treatment of thyroid malignancies, the procedure can be performed safely with acceptable morbidity.

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Year:  2004        PMID: 15091209     DOI: 10.1097/00005537-200403000-00002

Source DB:  PubMed          Journal:  Laryngoscope        ISSN: 0023-852X            Impact factor:   3.325


  16 in total

1.  In papillary thyroid cancer, preoperative central neck ultrasound detects only macroscopic surgical disease, but negative findings predict excellent long-term regional control and survival.

Authors:  Mauricio A Moreno; Beth S Edeiken-Monroe; Eric R Siegel; Steven I Sherman; Gary L Clayman
Journal:  Thyroid       Date:  2012-01-26       Impact factor: 6.568

2.  Pattern of initial metastasis in the cervical lymph node from papillary thyroid carcinoma.

Authors:  Naoyoshi Onoda; Tetsuro Ishikawa; Hidemi Kawajiri; Tsutomu Takashima; Kosei Hirakawa
Journal:  Surg Today       Date:  2012-06-26       Impact factor: 2.549

Review 3.  Lateral and mediastinal lymph node dissection in differentiated thyroid carcinoma: indications, benefits, and risks.

Authors:  Yasuhiro Ito; Akira Miyauchi
Journal:  World J Surg       Date:  2007-05       Impact factor: 3.352

4.  Risk factors for recurrence to the lymph node in papillary thyroid carcinoma patients without preoperatively detectable lateral node metastasis: validity of prophylactic modified radical neck dissection.

Authors:  Yasuhiro Ito; Takuya Higashiyama; Yuuki Takamura; Akihiro Miya; Kaoru Kobayashi; Fumio Matsuzuka; Kanji Kuma; Akira Miyauchi
Journal:  World J Surg       Date:  2007-11       Impact factor: 3.352

Review 5.  Individualized optimal surgical extent of the lateral neck in papillary thyroid cancer with lateral cervical metastasis.

Authors:  Jae-Yong Park; Bon Seok Koo
Journal:  Eur Arch Otorhinolaryngol       Date:  2013-07-16       Impact factor: 2.503

Review 6.  German Association of Endocrine Surgeons practice guideline for the surgical management of malignant thyroid tumors.

Authors:  Henning Dralle; Thomas J Musholt; Jochen Schabram; Thomas Steinmüller; Andreja Frilling; Dietmar Simon; Peter E Goretzki; Bruno Niederle; Christian Scheuba; Thomas Clerici; Michael Hermann; Jochen Kußmann; Kerstin Lorenz; Christoph Nies; Peter Schabram; Arnold Trupka; Andreas Zielke; Wolfram Karges; Markus Luster; Kurt W Schmid; Dirk Vordermark; Hans-Joachim Schmoll; Reinhard Mühlenberg; Otmar Schober; Harald Rimmele; Andreas Machens
Journal:  Langenbecks Arch Surg       Date:  2013-03-03       Impact factor: 3.445

7.  Extranodal extension of metastatic papillary thyroid carcinoma: correlation with biochemical endpoints, nodal persistence, and systemic disease progression.

Authors:  Miriam Lango; Douglas Flieder; Rodrigo Arrangoiz; Colleen Veloski; Jian Q Yu; Tianyu Li; Barbara Burtness; Ranee Mehra; Tom Galloway; John A Ridge
Journal:  Thyroid       Date:  2013-09       Impact factor: 6.568

Review 8.  Neck dissection with cervical sensory preservation in thyroid cancer.

Authors:  Shuai Xue; Peisong Wang; Guang Chen
Journal:  Gland Surg       Date:  2013-11

9.  Pattern of neck recurrence after lateral neck dissection for cervical metastases in papillary thyroid cancer.

Authors:  William F McNamara; Laura Y Wang; Frank L Palmer; Iain J Nixon; Jatin P Shah; Snehal G Patel; Ian Ganly
Journal:  Surgery       Date:  2016-03-16       Impact factor: 3.982

Review 10.  Lateral lymph node dissection guided by preoperative and intraoperative findings in differentiated thyroid carcinoma.

Authors:  Yasuhiro Ito; Akira Miyauchi
Journal:  World J Surg       Date:  2008-05       Impact factor: 3.352

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