Literature DB >> 15086744

Multiple, disseminated cutaneous metastases of vulvar squamous cell carcinoma.

F Ghaemmaghami1, M Modares, N Behtash, A Z Moosavi.   

Abstract

Cutaneous metastases of vulvar carcinoma are extremely rare and have been reported in six patients so far. Our patient, who is the seventh one, is a 38-year-old woman with a history of diabetes mellitus. After detecting stage III squamous cell carcinoma of the vulva, she underwent radical vulvectomy and bilateral inguinal lymphadenectomy. She received 6000 cGy external beam radiation for positive margins. Six months later, she came back with multiple advanced skin lesions. Biopsy was performed and lesions were confirmed as cutaneous metastases. For her palliation, some chemotherapy drugs were prescribed. She is on her sixth chemotherapy cycle, but these skin lesions are somewhat a preterminal event and there is no well-established treatment for this phase of disease.

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Year:  2004        PMID: 15086744     DOI: 10.1111/j.1048-891x.2004.014227.x

Source DB:  PubMed          Journal:  Int J Gynecol Cancer        ISSN: 1048-891X            Impact factor:   3.437


  2 in total

Review 1.  Cutaneous metastases of visceral tumours: a review.

Authors:  Dorothée Nashan; Marcel Lucas Müller; Markus Braun-Falco; Sebastian Reichenberger; Rolf-Markus Szeimies; Leena Bruckner-Tuderman
Journal:  J Cancer Res Clin Oncol       Date:  2008-06-17       Impact factor: 4.553

2.  Radiation port cutaneous metastases: reports of two patients whose recurrent visceral cancers presented as skin lesions at the site of previous radiation and literature review.

Authors:  Brian Spencer Hoyt; Philip Randolph Cohen
Journal:  Indian J Dermatol       Date:  2014-03       Impact factor: 1.494

  2 in total

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