Literature DB >> 1508570

Pregnancy in a quadriplegic patient treated with continuous intrathecal baclofen infusion to manage her severe spasticity. Case report.

E M Delhaas1, J Verhagen.   

Abstract

A report on pregnancy in a quadriplegic patient treated with a high dose of 1000 mcg/24 h continuous intrathecal baclofen infusion using an implanted drug delivery system (Synchromed, Medtronic, USA). Spasticity could be managed up to the 35th week of gestation. However, uterine contractions evoke enormous spastic symptoms which we, even with maximum values of the spasticity scales, could not classify. The recurrence of spasticity was associated with autonomic dysregulation. With continuous epidurally infused bupivacaine (11.25 mg/h) adequate relaxation could be reached and gestation was terminated by a primary caesarean section. A healthy girl was born (2040 g, Apgar 9 and 10).

Entities:  

Mesh:

Substances:

Year:  1992        PMID: 1508570     DOI: 10.1038/sc.1992.110

Source DB:  PubMed          Journal:  Paraplegia        ISSN: 0031-1758


  3 in total

1.  Intrathecal baclofen pump - a viable therapeutic option in pregnancy.

Authors:  Saira S Tandon; Iffath Hoskins; Salman Azhar
Journal:  Obstet Med       Date:  2010-09-17

Review 2.  A benefit-risk assessment of baclofen in severe spinal spasticity.

Authors:  Alessandro Dario; Giustino Tomei
Journal:  Drug Saf       Date:  2004       Impact factor: 5.606

3.  Pregnancy and Breastfeeding during Intrathecal Baclofen Therapy - A Case Study and Review.

Authors:  Takeshi Hara; Madoka Nakajima; Hidenori Sugano; Kostadin Karagiozov; Emiko Hirose; Keiko Goto; Hajime Arai
Journal:  NMC Case Rep J       Date:  2018-06-25
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.