| Literature DB >> 15085360 |
H-J Rupprecht1, S Genth-Zotz, W Jungmair, C Espinola-Klein, S Blankenberg, F Post.
Abstract
Antithrombotic therapy in acute coronary syndrome without ST-segment elevation should be initiated with aspirin 100 mg/day (loading dose 250-500 mg) and Clopidogrel 75 mg/day (loading dose 300 mg). In addition, anticoagulation with unfractionated heparin or low molecular weight heparin should be started. A GP IIb/IIIa receptor blocker can be given either upfront (Eptifibatide/Tirofiban) or directly in the cathlab preceding PCI (Abciximab). Aspirin should be given in the chronic phase lifelong, Clopidogrel for at least nine months. An invasive strategy is recommended in high-risk patients within 48 hours.Entities:
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Year: 2004 PMID: 15085360 DOI: 10.1007/s00392-004-1401-5
Source DB: PubMed Journal: Z Kardiol ISSN: 0300-5860