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Literature DB >> 15085190

Experimental autoimmune hearing loss.

Abstract

Understanding of autoimmune sensorineural hearing loss (ASNHL) has been hindered by the inaccessibility of the inner ear to biopsy and the lack of workable animal models. A report in this issue of the JCI describes a mouse model of CD4(+) T cell-mediated ASNHL induced by immunization with peptides from the inner ear-specific proteins cochlin and beta-tectorin.

Entities: Disease Gene Species

Mesh：

Substances：

Year: 2004 PMID： 15085190 PMCID： PMC385415 DOI： 10.1172/JCI21632

Source DB: PubMed Journal: J Clin Invest ISSN： 0021-9738 Impact factor: 14.808

16 in total

1. A rat T-cell line that mediates autoimmune disease of the inner ear in the Lewis rat.

Authors: B Gloddek; J Gloddek; W Arnold
Journal: ORL J Otorhinolaryngol Relat Spec Date: 1999 Jul-Aug Impact factor: 1.538

2. Experimental autoimmune inner ear disease: an electrocochleographic and histophysiologic study.

Authors: H Bouman; S F Klis; F Meeuwsen; J C de Groot; G F Smoorenburg; J E Veldman
Journal: Ann Otol Rhinol Laryngol Date: 2000-05 Impact factor: 1.547

3. No evidence of auditory dysfunction in guinea pigs immunized with myelin P0 protein.

Authors: M R Boulassel; J M Guérit; S Denison; M de Tourtchaninoff; L Wenderickx; N Botterman; N Deggouj; M Gersdorff; J P Tomasi
Journal: Hear Res Date: 2001-02 Impact factor: 3.208

4. COCH5B2 is a target antigen of anti-inner ear antibodies in autoimmune inner ear diseases.

Authors: M R Boulassel; J P Tomasi; N Deggouj; M Gersdorff
Journal: Otol Neurotol Date: 2001-09 Impact factor: 2.311

5. Experimental autoimmune labyrinthitis: assessment of molecular size of autoantigens in fractions of inner ear proteins eluted on the Mini Whole Gel Eluter.

Authors: Shunichi Tomiyama
Journal: Acta Otolaryngol Date: 2002-10 Impact factor: 1.494

6. Validity of the Western blot immunoassay for heat shock protein-70 in associated and isolated immunorelated inner ear disease.

Authors: José Ramón García Berrocal; Rafael Ramírez-Camacho; Beatriz Arellano; Juan Antonio Vargas
Journal: Laryngoscope Date: 2002-02 Impact factor: 3.325

7. Passive transfer of experimental autoimmune labyrinthitis.

Authors: T Ikezono; S Tomiyama; R Pawankar; K Jinnouchi; Y Suzuki; T Yagi
Journal: Audiol Neurootol Date: 2000 Sep-Oct Impact factor: 1.854

8. Murine autoimmune hearing loss mediated by CD4+ T cells specific for inner ear peptides.

Authors: C Arturo Solares; Andrea E Edling; Justin M Johnson; Moo-Jin Baek; Keiko Hirose; Gordon B Hughes; Vincent K Tuohy
Journal: J Clin Invest Date: 2004-04 Impact factor: 14.808

9. A novel class II-binding motif selects peptides that mediate organ-specific autoimmune disease in SWXJ, SJL/J, and SWR/J mice.

Authors: Daniel Jane-wit; Min Yu; Andrea E Edling; Seiko Kataoka; Justin M Johnson; Linda B Stull; Christine S Moravec; Vincent K Tuohy
Journal: J Immunol Date: 2002-12-01 Impact factor: 5.422

Experimental autoimmune hearing loss.

1. A rat T-cell line that mediates autoimmune disease of the inner ear in the Lewis rat.

2. Experimental autoimmune inner ear disease: an electrocochleographic and histophysiologic study.

3. No evidence of auditory dysfunction in guinea pigs immunized with myelin P0 protein.

4. COCH5B2 is a target antigen of anti-inner ear antibodies in autoimmune inner ear diseases.

5. Experimental autoimmune labyrinthitis: assessment of molecular size of autoantigens in fractions of inner ear proteins eluted on the Mini Whole Gel Eluter.

6. Validity of the Western blot immunoassay for heat shock protein-70 in associated and isolated immunorelated inner ear disease.

7. Passive transfer of experimental autoimmune labyrinthitis.

8. Murine autoimmune hearing loss mediated by CD4+ T cells specific for inner ear peptides.

9. A novel class II-binding motif selects peptides that mediate organ-specific autoimmune disease in SWXJ, SJL/J, and SWR/J mice.

10. A reexamination of experimental type II collagen autoimmunity: middle and inner ear morphology and function.

1. Sensorineural hearing loss in patients with inflammatory bowel disease: a subclinical extraintestinal manifestation.

Review 2. New prospects in the diagnosis and treatment of immune-mediated inner ear disease.

3. Assessment of Hearing Function in Children with Inflammatory Bowel Disease.

4. Sensorineural hearing loss in pediatric patients with celiac disease.

5. Sensorineural hearing loss in pediatric patients with inflammatory bowel disease.

Review 6. The Role of Autoimmunity in the Pathogenesis of Sudden Sensorineural Hearing Loss.