BACKGROUND: Opinion is divided regarding the optimal method of biliary reconstruction after liver transplantation for primary sclerosing cholangitis (PSC). METHODS: We investigated biliary complications and graft and patient survival in all patients who underwent liver transplantation for PSC in the United Kingdom between 1994 and 2003. RESULTS: Anastomotic leak rates were similar, but a significantly higher stricture rate was observed in patients who had a duct-to-duct reconstruction compared with those who underwent a Roux-en-Y anastomosis. Graft and patient survival were also markedly worse in patients with a duct-to-duct anastomosis. CONCLUSIONS: Roux-en-Y choledochojejunostomy is the method of choice for biliary reconstruction in liver transplantation for PSC.
BACKGROUND: Opinion is divided regarding the optimal method of biliary reconstruction after liver transplantation for primary sclerosing cholangitis (PSC). METHODS: We investigated biliary complications and graft and patient survival in all patients who underwent liver transplantation for PSC in the United Kingdom between 1994 and 2003. RESULTS:Anastomotic leak rates were similar, but a significantly higher stricture rate was observed in patients who had a duct-to-duct reconstruction compared with those who underwent a Roux-en-Y anastomosis. Graft and patient survival were also markedly worse in patients with a duct-to-duct anastomosis. CONCLUSIONS: Roux-en-Y choledochojejunostomy is the method of choice for biliary reconstruction in liver transplantation for PSC.
Authors: Stefan Kienlein; Wenzel Schoening; Anne Andert; Daniela Kroy; Ulf Peter Neumann; Maximilian Schmeding Journal: World J Transplant Date: 2015-12-24
Authors: John E Eaton; Jayant A Talwalkar; Konstantinos N Lazaridis; Gregory J Gores; Keith D Lindor Journal: Gastroenterology Date: 2013-07-01 Impact factor: 22.682
Authors: William Bennet; Michael A Zimmerman; Jeffrey Campsen; Mercedes Susan Mandell; Tom Bak; Michael Wachs; Igal Kam Journal: World J Surg Date: 2009-05 Impact factor: 3.352