| Literature DB >> 15083378 |
Abstract
The recent studies on humans with a defective gene that encodes aromatase p450 (p450arom) and aromatase knockout (ArKO) mice with a disrupted p450arom gene uncovered many interesting aspects of physiology. Aromatase-deficient humans and ArKO mice continue to serve as invaluable models for us to study the roles of estrogen in normal and abnormal functions of several tissues. These roles will be discussed in detail in the following review article.Entities:
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Year: 2004 PMID: 15083378 DOI: 10.1055/s-2004-823024
Source DB: PubMed Journal: Semin Reprod Med ISSN: 1526-4564 Impact factor: 1.303