Literature DB >> 15082275

Repair of transposition of the great arteries, ventricular septal defect and left ventricular outflow tract obstruction.

Jeong Ryul Lee1, Hong Gook Lim, Yong Jin Kim, Joon Ryang Rho, Eun Jung Bae, Chung Il Noh, Yong Soo Yun, Curie Ahn.   

Abstract

OBJECTIVES: This study was undertaken to compare the outcomes of the Lecompte procedure and Rastelli repair in the transposition of the great arteries (TGA) with ventricular septal defect (VSD) and left ventricular outflow tract obstruction (LVOTO) and to determine the risk factors associated with unfavorable events.
METHODS: Over a 12-year period (April 1990-October 2002), 35 patients underwent complete repair for TGA, VSD, and LVOTO. Twenty-five patients (71%) underwent the Lecompte modification, and mean age and weight were 23.4+/-18.2 months and 10.2+/-3.0 kg. Ten patients (29%) underwent the Rastelli operation, and mean age and weight were 39.1+/-36.1 months and 13.8+/-6.8 kg.
RESULTS: One early death (3%) occurred after the Lecompte procedure and no late death. The mean follow-up was 5.9+/-3.8 years. Eight patients in the Rastelli group (80%) underwent a late reoperation for obstruction of the extracardiac conduit, and in four of these patients, a reoperation for LVOTO was concomitantly required. Reoperation was also required in six patients of the Lecompte group (25%); five for right ventricular outflow tract obstruction (RVOTO) including one for LVOTO and two for VSD leakage, and one for mitral regurgitation and left pulmonary artery stenosis. The interval prior to reoperation ranged from 1.6 to 11.1 years, with a mean of 5.7+/-3.1 years. The actuarial figures for freedom from reoperation at 5 and 10 years were 40.0+/-15.5 and 26.7+/-15.0% after the Rastelli operation and 95.7+/-4.3 and 63.5+/-12.6% after the Lecompte procedure (P = 0.02). Multivariate analysis by Cox regression analysis revealed that the risk factors of RVOTO were a younger age at operation, the Rastelli operation, and ductus ligation during the operation.
CONCLUSIONS: The Lecompte procedure and Rastelli repair provide satisfactory early and late results. However, substantial late morbidity is more associated with conduit obstruction, and LVOTO in Rastelli repair rather than Lecompte procedure.

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Year:  2004        PMID: 15082275     DOI: 10.1016/j.ejcts.2004.01.001

Source DB:  PubMed          Journal:  Eur J Cardiothorac Surg        ISSN: 1010-7940            Impact factor:   4.191


  5 in total

1.  Abnormal mitral valve anatomy in d-transposition of the great arteries: anatomic characterization and surgical outcomes.

Authors:  Joseph A Camarda; Susan E Harris; John Hambrook; Michele A Frommelt; James S Tweddell; Peter C Frommelt
Journal:  Pediatr Cardiol       Date:  2012-06-04       Impact factor: 1.655

2.  D-Transposition of the Great Arteries with Ventricular Septal Defect and Left Ventricular Outflow Tract Obstruction (D-TGA/VSD/LVOTO): A Survey of Perceptions, Preferences, and Experience.

Authors:  Mohammed K Al-Jughiman; Maryam A Al-Omair; Glen S Van Arsdell; Victor O Morell; Marshall L Jacobs
Journal:  Pediatr Cardiol       Date:  2015-02-03       Impact factor: 1.655

3.  Alternatives to conduits.

Authors:  Krishna S Iyer
Journal:  Ann Pediatr Cardiol       Date:  2008-01

4.  Options for coronary translocation and other considerations in aortic root translocation (Bex-Nikaidoh procedure).

Authors:  Swaminathan Vaidyanathan; Marathe Supreet; Marathe Shilpa; Alphonso Nelson; Agarwal Vijay
Journal:  Ann Pediatr Cardiol       Date:  2019 Sep-Dec

Review 5.  Transposition of the great arteries.

Authors:  Paula Martins; Eduardo Castela
Journal:  Orphanet J Rare Dis       Date:  2008-10-13       Impact factor: 4.123

  5 in total

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