| Literature DB >> 15081527 |
Nancy Hogg1, Andrew Smith, Alison McDowall, Katherine Giles, Paula Stanley, Melanie Laschinger, Robert Henderson.
Abstract
The T lymphocyte (or T cell) has classically been perceived to be a passive circular cell attaching to other cells or fibrils of the extracellular matrix when its integrins become activated. We now understand that the modus operandi of the T cell is migration. These cells are proving to be impressively fast migrators, clocking up basal speeds of approximately 10-15 microm/min which makes them amongst the fastest movers recorded to date. Therefore, migration is the business of the T cell and in this review we will discuss how its motility is regulated and what functions this activity makes possible.Entities:
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Year: 2004 PMID： 15081527 DOI： 10.1016/j.imlet.2003.10.014
Source DB: PubMed Journal: Immunol Lett ISSN： 0165-2478 Impact factor: 3.685