Literature DB >> 15081457

Bradycardia during therapy for multiple myeloma with thalidomide.

Ibrahim Elias Fahdi1, Venkat Gaddam, Jorge F Saucedo, Channarayapatna V Kishan, Keyur Vyas, Matthew G Deneke, Hani Razek, Brett Thorn, Joseph K Bissett, Elias J Anaissie, Elias Anaisse, Bart Barlogie, Jawahar L Mehta.   

Abstract

We studied the medical records of 96 patients who received thalidomide and 104 patients who made up a control group. We found that 53% of patients (52 patients) using thalidomide had a heart rate of <60 beats/min at some point during follow-up and 19% of thalidomide patients (10 patients) developed symptom-related bradycardia. Reducing the thalidomide dose appeared to alleviate symptoms in most patients.

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Year:  2004        PMID: 15081457     DOI: 10.1016/j.amjcard.2003.12.061

Source DB:  PubMed          Journal:  Am J Cardiol        ISSN: 0002-9149            Impact factor:   2.778


  11 in total

1.  Thalidomide-induced symptomatic third-degree atrioventricular block.

Authors:  M Hinterseer; A Becker; S Kääb; N Lang; M Näbauer; G Steinbeck
Journal:  Clin Res Cardiol       Date:  2006-06-20       Impact factor: 5.460

Review 2.  Cancer chemotherapy and cardiac arrhythmias: a review.

Authors:  Juan Tamargo; Ricardo Caballero; Eva Delpón
Journal:  Drug Saf       Date:  2015-02       Impact factor: 5.606

Review 3.  Cancer Chemotherapy-Induced Sinus Bradycardia: A Narrative Review of a Forgotten Adverse Effect of Cardiotoxicity.

Authors:  Juan Tamargo; Ricardo Caballero; Eva Delpón
Journal:  Drug Saf       Date:  2022-01-13       Impact factor: 5.606

4.  Thalidomide causes sinus bradycardia in ALS.

Authors:  Thomas Meyer; André Maier; Nadja Borisow; Jörn S Dullinger; Gerald Splettstösser; Stephanie Ohlraun; Christoph Münch; Peter Linke
Journal:  J Neurol       Date:  2008-04-21       Impact factor: 4.849

5.  Peripheral neuropathy associated with novel therapies in patients with multiple myeloma: consensus statement of the IMF Nurse Leadership Board.

Authors:  Joseph D Tariman; Ginger Love; Emily McCullagh; Stacey Sandifer
Journal:  Clin J Oncol Nurs       Date:  2008-06       Impact factor: 1.027

Review 6.  Mechanisms of Cardiotoxicity of Cancer Chemotherapeutic Agents: Cardiomyopathy and Beyond.

Authors:  Rohit Moudgil; Edward T H Yeh
Journal:  Can J Cardiol       Date:  2016-02-02       Impact factor: 5.223

Review 7.  Electrophysiologic Toxicity of Chemoradiation.

Authors:  Merna A Armanious; Shreya Mishra; Michael G Fradley
Journal:  Curr Oncol Rep       Date:  2018-04-11       Impact factor: 5.075

8.  Community-acquired lung abscess caused by Legionella micdadei in a myeloma patient receiving thalidomide treatment.

Authors:  Louis P Girard; Daniel B Gregson
Journal:  J Clin Microbiol       Date:  2007-07-03       Impact factor: 5.948

9.  Myocardial infarction, symptomatic third degree atrioventricular block and pulmonary embolism caused by thalidomide: a case report.

Authors:  Shengyu Zhang; Jing Yang; Xiaofeng Jin; Shuyang Zhang
Journal:  BMC Cardiovasc Disord       Date:  2015-12-18       Impact factor: 2.298

Review 10.  Onco-Cardiology: Consensus Paper of the German Cardiac Society, the German Society for Pediatric Cardiology and Congenital Heart Defects and the German Society for Hematology and Medical Oncology.

Authors:  Tienush Rassaf; Matthias Totzeck; Johannes Backs; Carsten Bokemeyer; Michael Hallek; Denise Hilfiker-Kleiner; Andreas Hochhaus; Diana Lüftner; Oliver J Müller; Ulrich Neudorf; Roman Pfister; Stephan von Haehling; Lorenz H Lehmann; Johann Bauersachs
Journal:  Clin Res Cardiol       Date:  2020-05-13       Impact factor: 5.460

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