Literature DB >> 15081050

Transgene integration in plants: poking or patching holes in promiscuous genomes?

David A Somers1, Irina Makarevitch.   

Abstract

Transgene integration in plants transformed by either Agrobacterium or direct DNA delivery methods occurs through illegitimate recombination (IR). The precise mechanism(s) for IR-mediated transgene integration and the role of host double-strand break repair enzymes remain unknown. A recent wealth of sequenced transgene loci and investigations aimed at genetically dissecting transgene integration mechanism(s) have provided new insights into the process.

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Year:  2004        PMID： 15081050     DOI： 10.1016/j.copbio.2004.02.007

Source DB:  PubMed          Journal:  Curr Opin Biotechnol        ISSN： 0958-1669            Impact factor:   9.740


  12 in total

1.  Characterisation of 3' transgene insertion site and derived mRNAs in MON810 YieldGard maize.

Authors:  Alessio Rosati; Patrizia Bogani; Alisa Santarlasci; Marcello Buiatti
Journal:  Plant Mol Biol       Date:  2008-06       Impact factor: 4.076

Review 2.  Enhancing gene targeting efficiency in higher plants: rice is on the move.

Authors:  Olivier Cotsaftis; Emmanuel Guiderdoni
Journal:  Transgenic Res       Date:  2005-02       Impact factor: 2.788

3.  Mechanism of random integration of foreign DNA in transgenic mice.

Authors:  Bo-Wen Yan; Yao-Feng Zhao; Wen-Guang Cao; Ning Li; Ke-Mian Gou
Journal:  Transgenic Res       Date:  2013-03-13       Impact factor: 2.788

4.  Gene targeting by homologous recombination as a biotechnological tool for rice functional genomics.

Authors:  Rie Terada; Yasuyo Johzuka-Hisatomi; Miho Saitoh; Hisayo Asao; Shigeru Iida
Journal:  Plant Physiol       Date:  2007-04-20       Impact factor: 8.340

5.  Genetic approaches for studying transgene inheritance and genetic recombination in three successive generations of transformed tobacco.

Authors:  Kalthoum Tizaoui; Mohamed Elyes Kchouk
Journal:  Genet Mol Biol       Date:  2012-08-17       Impact factor: 1.771

6.  The mutational consequences of plant transformation.

Authors:  Jonathan R Latham; Allison K Wilson; Ricarda A Steinbrecher
Journal:  J Biomed Biotechnol       Date:  2006

7.  In situ methods to localize transgenes and transcripts in interphase nuclei: a tool for transgenic plant research.

Authors:  Ana Paula Santos; Eva Wegel; George C Allen; William F Thompson; Eva Stoger; Peter Shaw; Rita Abranches
Journal:  Plant Methods       Date:  2006-11-02       Impact factor: 4.993

Review 8.  A comparative analysis of insertional effects in genetically engineered plants: considerations for pre-market assessments.

Authors:  Jaimie Schnell; Marina Steele; Jordan Bean; Margaret Neuspiel; Cécile Girard; Nataliya Dormann; Cindy Pearson; Annie Savoie; Luc Bourbonnière; Philip Macdonald
Journal:  Transgenic Res       Date:  2014-10-26       Impact factor: 2.788

Review 9.  Sugarcane Water Stress Tolerance Mechanisms and Its Implications on Developing Biotechnology Solutions.

Authors:  Thais H S Ferreira; Max S Tsunada; Denis Bassi; Pedro Araújo; Lucia Mattiello; Giovanna V Guidelli; Germanna L Righetto; Vanessa R Gonçalves; Prakash Lakshmanan; Marcelo Menossi
Journal:  Front Plant Sci       Date:  2017-06-23       Impact factor: 5.753

10.  Agrobacterium-mediated transformation of tomato elicits unexpected flower phenotypes with similar gene expression profiles.

Authors:  Yi-Hong Wang; Michael A Campbell
Journal:  PLoS One       Date:  2008-08-13       Impact factor: 3.240
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