| Literature DB >> 15080976 |
Ravi Kurukulasuriya1, Bryan K Sorensen, James T Link, Jyoti R Patel, Hwan-Soo Jae, Marty X Winn, Jeffrey R Rohde, Nelson D Grihalde, Chun W Lin, Christopher A Ogiela, Andrew L Adler, Christine A Collins.
Abstract
Biaryl amides derived from a reported series of ureas 1 were evaluated and found to be potent human glucagon receptor antagonists. The benzofuran analogue 6i was administered in Sprague-Dawley rats and blocked the effects of an exogenous glucagon challenge.Entities:
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Year: 2004 PMID： 15080976 DOI： 10.1016/j.bmcl.2004.02.056
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823