| Literature DB >> 15080974 |
Chinnian J Magesh1, Sarasu V Makesh, Paramasivan T Perumal.
Abstract
The first, target-oriented synthesis of pyranoquinolines as potential antibacterial agents by inverse electron demand (IED) Diels-Alder reaction using chiral salen-AlCl complex has been accomplished, the reactions proceed with moderate yields, and a very high degree of diastereoselectivity (>90%). The diastereoselectivity-enhanced pyranoquinolines exhibit potential bactericidal activity against seven strains of pathogenic gram-negative bacteria.Entities:
Mesh：
Substances：
Year: 2004 PMID： 15080974 DOI： 10.1016/j.bmcl.2004.02.057
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823