| Literature DB >> 15080910 |
S Batra1, A K Roy, A Patra, A P Bhaduri, W R Surin, S A V Raghavan, P Sharma, K Kapoor, M Dikshit.
Abstract
The solution-phase parallel synthesis involving reactions of Baylis-Hillman products of 3-substituted-5-isoxazolecarbaldehydes with nucleophiles and their in vivo antithrombotic evaluations are described along with the results of in vitro platelet aggregation inhibition assay of a few compounds. Results of the detailed evaluation of one of the compounds as an inhibitor of platelet aggregation are also presented.Entities:
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Year: 2004 PMID： 15080910 DOI： 10.1016/j.bmc.2004.02.023
Source DB: PubMed Journal: Bioorg Med Chem ISSN： 0968-0896 Impact factor: 3.641