Literature DB >> 15079093

The influence of cardiopulmonary bypass on respiratory dysfunction in early postoperative period.

Judita Andrejaitiene1, Edmundas Sirvinskas, Ramūnas Bolys.   

Abstract

BACKGROUND AND
OBJECTIVE: Pulmonary dysfunction is one of the most serious problems in an early postoperative period after cardiac surgery. This study was designed to reveal the impact of performed cardiopulmonary bypass on pulmonary function during early postoperative period by evaluating the intrapulmonary shunt.
MATERIAL AND METHODS: Twenty-one patients undergoing elective myocardial revascularization surgery were analyzed. The patients were divided into two groups. Group 1 included 11 patients who underwent cardiac surgery on cardiopulmonary bypass. Group 2 included 10 patients who underwent cardiac surgery without cardiopulmonary bypass. Preoperative data were similar in the both groups. Blood gas analysis for intrapulmonary shunt calculations was made at 20 minutes after the induction of anesthesia and at 4 hours after the surgery. Intrapulmonary shunt size (Qs/Qt) was also calculated and the records were studied for additional data.
RESULTS: At 4 hours after surgery Qs/Qt increased, compared to the preoperative data in Group 1 (from 8.6+/-2.1 to 16.8+/-2.6%, p<0.02). Intrapulmonary shunt was great in Group 1 compared with Group 2 at four hours after the surgery (16.8+/-2.6 and 7.8+/-2.1%, p<0.02). In Group 1 80 % of alterations in a pulmonary function were caused by atelectasis, detected by chest X-ray. In Group 2 no increase in intrapulmonary shunt and no atelectasis were determined.
CONCLUSIONS: Arterial hypoxemia and increase in intrapulmonary shunt (due to atelectasis) have proven that alterations in pulmonary function are found more often and are more pronounced in patients after surgery on cardiopulmonary bypass.

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Mesh:

Year:  2004        PMID: 15079093

Source DB:  PubMed          Journal:  Medicina (Kaunas)        ISSN: 1010-660X            Impact factor:   2.430


  3 in total

1.  Frequency Rate of Atelectasis in Patients Following Coronary Artery Bypass Graft and Its Associated Factors at Mazandaran Heart Center in 2013-2014.

Authors:  Neshat Hasan Niyayeh Saffari; Ebrahim Nasiri; Seyed Nouraddin Mousavinasab; Rahman Ghafari; Aria Soleimani; Ravanbakhsh Esmaeili
Journal:  Glob J Health Sci       Date:  2015-03-26

2.  The Effect of Low Tidal Volume Ventilation during Cardiopulmonary Bypass on Postoperative Pulmonary Function.

Authors:  Maryam Davoudi; Afshin Farhanchi; Ahmad Moradi; Mohammad Hosein Bakhshaei; Gholamreza Safarpour
Journal:  J Tehran Heart Cent       Date:  2010-08-31

3.  Elevated free fatty acid level is a risk factor for early postoperative hypoxemia after on-pump coronary artery bypass grafting: association with endothelial activation.

Authors:  Sheng Shi; Yuan Gao; Limin Wang; Jian Liu; Zhongxiang Yuan; Min Yu
Journal:  J Cardiothorac Surg       Date:  2015-09-17       Impact factor: 1.637

  3 in total

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