Literature DB >> 15079068

A possible therapeutic target for Lou Gehrig's disease.

Soumya S Ray1, Peter T Lansbury.   

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Year:  2004        PMID： 15079068      PMCID： PMC395856          DOI： 10.1073/pnas.0401934101

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


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  23 in total

Review 1.  Protofibrils, pores, fibrils, and neurodegeneration: separating the responsible protein aggregates from the innocent bystanders.

Authors:  Byron Caughey; Peter T Lansbury
Journal:  Annu Rev Neurosci       Date:  2003-04-09       Impact factor: 12.449

2.  Common denominator of Cu/Zn superoxide dismutase mutants associated with amyotrophic lateral sclerosis: decreased stability of the apo state.

Authors:  Mikael J Lindberg; Lena Tibell; Mikael Oliveberg
Journal:  Proc Natl Acad Sci U S A       Date:  2002-12-13       Impact factor: 11.205

3.  Cu/Zn superoxide dismutase can form pore-like structures.

Authors:  Jinhyuk Chung; Hoichang Yang; Mitchel D de Beus; Chang Y Ryu; Kilwon Cho; Wilfredo Colón
Journal:  Biochem Biophys Res Commun       Date:  2003-12-26       Impact factor: 3.575

4.  Cu/Zn superoxide dismutase mutants associated with amyotrophic lateral sclerosis show enhanced formation of aggregates in vitro.

Authors:  P B Stathopulos; J A O Rumfeldt; G A Scholz; R A Irani; H E Frey; R A Hallewell; J R Lepock; E M Meiering
Journal:  Proc Natl Acad Sci U S A       Date:  2003-05-28       Impact factor: 11.205

5.  Dimer destabilization in superoxide dismutase may result in disease-causing properties: structures of motor neuron disease mutants.

Authors:  Michael A Hough; J Günter Grossmann; Svetlana V Antonyuk; Richard W Strange; Peter A Doucette; Jorge A Rodriguez; Lisa J Whitson; P John Hart; Lawrence J Hayward; Joan Selverstone Valentine; S Samar Hasnain
Journal:  Proc Natl Acad Sci U S A       Date:  2004-03-31       Impact factor: 11.205

6.  ALS mutants of human superoxide dismutase form fibrous aggregates via framework destabilization.

Authors:  Michael DiDonato; Lisa Craig; Mary E Huff; Maria M Thayer; Rosa M F Cardoso; Carey J Kassmann; Terence P Lo; Cami K Bruns; Evan T Powers; Jeffery W Kelly; Elizabeth D Getzoff; John A Tainer
Journal:  J Mol Biol       Date:  2003-09-19       Impact factor: 5.469

7.  Copper-binding-site-null SOD1 causes ALS in transgenic mice: aggregates of non-native SOD1 delineate a common feature.

Authors:  Jiou Wang; Hilda Slunt; Victoria Gonzales; David Fromholt; Michael Coonfield; Neal G Copeland; Nancy A Jenkins; David R Borchelt
Journal:  Hum Mol Genet       Date:  2003-09-09       Impact factor: 6.150

8.  Superoxide dismutase folding/unfolding pathway: role of the metal ions in modulating structural and dynamical features.

Authors:  Michael Assfalg; Lucia Banci; Ivano Bertini; Paola Turano; Paul R Vasos
Journal:  J Mol Biol       Date:  2003-06-27       Impact factor: 5.469

Review 9.  Misfolded CuZnSOD and amyotrophic lateral sclerosis.

Authors:  Joan Selverstone Valentine; P John Hart
Journal:  Proc Natl Acad Sci U S A       Date:  2003-03-24       Impact factor: 11.205

10.  Tissue damage in the amyloidoses: Transthyretin monomers and nonnative oligomers are the major cytotoxic species in tissue culture.

Authors:  Natàlia Reixach; Songpon Deechongkit; Xin Jiang; Jeffery W Kelly; Joel N Buxbaum
Journal:  Proc Natl Acad Sci U S A       Date:  2004-02-23       Impact factor: 11.205
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  11 in total

1.  Improving binding specificity of pharmacological chaperones that target mutant superoxide dismutase-1 linked to familial amyotrophic lateral sclerosis using computational methods.

Authors:  Richard J Nowak; Gregory D Cuny; Sungwoon Choi; Peter T Lansbury; Soumya S Ray
Journal:  J Med Chem       Date:  2010-04-08       Impact factor: 7.446

2.  Strategies for stabilizing superoxide dismutase (SOD1), the protein destabilized in the most common form of familial amyotrophic lateral sclerosis.

Authors:  Jared R Auclair; Kristin J Boggio; Gregory A Petsko; Dagmar Ringe; Jeffrey N Agar
Journal:  Proc Natl Acad Sci U S A       Date:  2010-11-22       Impact factor: 11.205

Review 3.  Emerging mechanisms of molecular pathology in ALS.

Authors:  Owen M Peters; Mehdi Ghasemi; Robert H Brown
Journal:  J Clin Invest       Date:  2015-05-01       Impact factor: 14.808

4.  Cloning and molecular characterization of delta12-fatty acid desaturase gene from Mortierella isabellina.

Authors:  Ming-Chun Li; Hang Li; Dong-Sheng Wei; Lai-Jun Xing
Journal:  World J Gastroenterol       Date:  2006-06-07       Impact factor: 5.742

5.  Regulation of the aggregation behavior of human islet amyloid polypeptide fragment by titanocene complexes.

Authors:  Weihong Du; Gehui Gong; Wenji Wang; Jufei Xu
Journal:  J Biol Inorg Chem       Date:  2017-08-11       Impact factor: 3.358

6.  Cis-suppression to arrest protein aggregation in mammalian cells.

Authors:  Simpson Gregoire; Shaojie Zhang; Joseph Costanzo; Kelly Wilson; Erik J Fernandez; Inchan Kwon
Journal:  Biotechnol Bioeng       Date:  2013-10-18       Impact factor: 4.530

7.  Loss of SOD1 and LYS7 sensitizes Saccharomyces cerevisiae to hydroxyurea and DNA damage agents and downregulates MEC1 pathway effectors.

Authors:  Carole D Carter; Lauren E Kitchen; Wei-Chun Au; Christopher M Babic; Munira A Basrai
Journal:  Mol Cell Biol       Date:  2005-12       Impact factor: 4.272

8.  Small-molecule-mediated stabilization of familial amyotrophic lateral sclerosis-linked superoxide dismutase mutants against unfolding and aggregation.

Authors:  Soumya S Ray; Richard J Nowak; Robert H Brown; Peter T Lansbury
Journal:  Proc Natl Acad Sci U S A       Date:  2005-02-28       Impact factor: 11.205

9.  Amyloidogenic regions and interaction surfaces overlap in globular proteins related to conformational diseases.

Authors:  Virginia Castillo; Salvador Ventura
Journal:  PLoS Comput Biol       Date:  2009-08-21       Impact factor: 4.475

10.  Ligand binding and aggregation of pathogenic SOD1.

Authors:  Gareth S A Wright; Svetlana V Antonyuk; Neil M Kershaw; Richard W Strange; S Samar Hasnain
Journal:  Nat Commun       Date:  2013       Impact factor: 14.919
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