Literature DB >> 15075681

National Association of Medical Examiners position paper on the certification of cocaine-related deaths.

Boyd G Stephens1, Jeffrey M Jentzen, Steven Karch, Charles V Wetli, Deborah C Mash.   

Abstract

The National Association of Medical Examiners Committee on Cocaine-related Deaths recommends that the following guidelines be applied in the process of documenting, interpreting, and certifying potential cocaine-related fatalities. The committee cautions that the investigation of any drug-related death requires a complete investigation of the circumstances of death, the death scene, and past medical history. It is also necessary to have the results of the forensic toxicological analysis and those of a complete forensic autopsy examination prior to formulating an opinion as to the cause and manner of death. Cocaine should be considered the underlying cause of the death when 1 or more of the following is true: (1). the circumstances surrounding the death can be associated with an acute cocaine exposure and there are no supervening causes of death; (2). the immediate cause of death is directly due to a readily identifiable mechanism or disease such as a gunshot wound or a stroke, yet the acute use of cocaine was the direct underlying cause of the trauma or the disease process; and (3). chronic cocaine use leads to a disease that results in an ultimately fatal pathologic process leading to organ injury and death. The committee further cautions that reported drug levels may not directly relate to the toxic or lethal effects of the drug upon the patient. These guidelines are intended for use by practicing medical examiners and physicians who certify drug deaths, as well as providing education tools for students.

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Year:  2004        PMID: 15075681     DOI: 10.1097/01.paf.0000114041.70865.24

Source DB:  PubMed          Journal:  Am J Forensic Med Pathol        ISSN: 0195-7910            Impact factor:   0.921


  14 in total

1.  Case files of the medical toxicology fellowship training program at the New York city poison control center: hypotensive death--therapeutic complication or suicide?

Authors:  S Eliza Halcomb; Lewis S Nelson
Journal:  J Med Toxicol       Date:  2006-06

Review 2.  Back to the Future - Part 1. The medico-legal autopsy from ancient civilization to the post-genomic era.

Authors:  Giovanni Cecchetto; Thomas Bajanowski; Rossana Cecchi; Donata Favretto; Silke Grabherr; Takaki Ishikawa; Toshikazu Kondo; Massimo Montisci; Heidi Pfeiffer; Maurizio Rippa Bonati; Dina Shokry; Marielle Vennemann; Santo Davide Ferrara
Journal:  Int J Legal Med       Date:  2017-04-24       Impact factor: 2.686

3.  Common human 5' dopamine transporter (SLC6A3) haplotypes yield varying expression levels in vivo.

Authors:  Tomas Drgon; Zhicheng Lin; Gene-Jack Wang; Joanna Fowler; Johnfn Pablo; Deborah C Mash; Nora Volkow; George R Uhl
Journal:  Cell Mol Neurobiol       Date:  2006-05-20       Impact factor: 5.046

4.  Cytosolic proteomic alterations in the nucleus accumbens of cocaine overdose victims.

Authors:  N Tannu; D C Mash; S E Hemby
Journal:  Mol Psychiatry       Date:  2006-10-31       Impact factor: 15.992

5.  Using poison center exposure calls to predict methadone poisoning deaths.

Authors:  Nabarun Dasgupta; Jonathan Davis; Michele Jonsson Funk; Richard Dart
Journal:  PLoS One       Date:  2012-07-19       Impact factor: 3.240

6.  GABAergic gene expression in postmortem hippocampus from alcoholics and cocaine addicts; corresponding findings in alcohol-naïve P and NP rats.

Authors:  Mary-Anne Enoch; Zhifeng Zhou; Mitsuru Kimura; Deborah C Mash; Qiaoping Yuan; David Goldman
Journal:  PLoS One       Date:  2012-01-13       Impact factor: 3.240

7.  Uniform standards and case definitions for classifying opioid-related deaths: recommendations by a SAMHSA consensus panel.

Authors:  Bruce A Goldberger; Jane Carlisle Maxwell; Anthony Campbell; Bonnie B Wilford
Journal:  J Addict Dis       Date:  2013

8.  Dopamine transporter DAT and receptor DRD2 variants affect risk of lethal cocaine abuse: a gene-gene-environment interaction.

Authors:  D Sullivan; J K Pinsonneault; A C Papp; H Zhu; S Lemeshow; D C Mash; W Sadee
Journal:  Transl Psychiatry       Date:  2013-01-22       Impact factor: 6.222

9.  Gene expression in human hippocampus from cocaine abusers identifies genes which regulate extracellular matrix remodeling.

Authors:  Deborah C Mash; Jarlath ffrench-Mullen; Nikhil Adi; Yujing Qin; Andrew Buck; John Pablo
Journal:  PLoS One       Date:  2007-11-14       Impact factor: 3.240

10.  RNA sequencing of transcriptomes in human brain regions: protein-coding and non-coding RNAs, isoforms and alleles.

Authors:  Amy Webb; Audrey C Papp; Amanda Curtis; Leslie C Newman; Maciej Pietrzak; Michal Seweryn; Samuel K Handelman; Grzegorz A Rempala; Daqing Wang; Erica Graziosa; Rachel F Tyndale; Caryn Lerman; John R Kelsoe; Deborah C Mash; Wolfgang Sadee
Journal:  BMC Genomics       Date:  2015-11-23       Impact factor: 3.969

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