Literature DB >> 15074953

Leucosceptrine--a novel sesterterpene with prolylendopeptidase inhibitory activity from Leucosceptrum canum.

Muhammad Iqbal Choudhary1, Rosa Ranjit, Atta-Ur-Rahman Atta-Ur-Rahman, Tirtha Maiya Shrestha, Amsha Yasin, Masood Parvez.   

Abstract

A novel sesterterpene, leucosceptrine, was isolated from the medicinal plant Leucosceptrum canum from Nepal. The structure was determined by single-crystal X-ray diffraction and spectroscopic techniques. The biosynthesis of leucosceptrine (1) is proposed here. Leucosceptrine (1) exhibited prolylendopeptidase inhibitory activity.

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Year:  2004        PMID： 15074953     DOI： 10.1021/jo030337u

Source DB:  PubMed          Journal:  J Org Chem        ISSN： 0022-3263            Impact factor:   4.354


  2 in total

1.  A Geranylfarnesyl Diphosphate Synthase Provides the Precursor for Sesterterpenoid (C25) Formation in the Glandular Trichomes of the Mint Species Leucosceptrum canum.

Authors:  Yan Liu; Shi-Hong Luo; Axel Schmidt; Guo-Dong Wang; Gui-Ling Sun; Marcus Grant; Ce Kuang; Min-Jie Yang; Shu-Xi Jing; Chun-Huan Li; Bernd Schneider; Jonathan Gershenzon; Sheng-Hong Li
Journal:  Plant Cell       Date:  2016-03-03       Impact factor: 11.277

2.  Cytotoxic sesterterpenoids isolated from the marine sponge Scalarispongia sp.

Authors:  Yeon-Ju Lee; Jeong-Woo Lee; Dong-Geun Lee; Hyi-Seung Lee; Jong Soon Kang; Jieun Yun
Journal:  Int J Mol Sci       Date:  2014-11-04       Impact factor: 5.923
  2 in total

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