Literature DB >> 15072136

Detection of polymorphisms in the prion protein gene in the Belgian sheep population: some preliminary data.

S Roels1, C Renard, H De Bosschere, R Geeroms, M Van Poucke, L Peelman, E Vanopdenbosch.   

Abstract

The development of clinical signs of TSE/scrapie in sheep has been linked to polymorphisms in the prion protein (PRNP) gene. The most important polymorphisms appear to be at codons 136, 154, and 171. The objective of this study was to investigate the polymorphisms at these codons in the Belgian sheep population, including clinical healthy animals, healthy animals at the slaughterhouse and animals in TSE/scrapie positive farms (including a Nor98 farm).

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Year:  2004        PMID： 15072136     DOI： 10.1080/01652176.2004.9695163

Source DB:  PubMed          Journal:  Vet Q        ISSN： 0165-2176            Impact factor:   3.320


  4 in total

Review 1.  Molecular Mechanisms of Chronic Wasting Disease Prion Propagation.

Authors:  Julie A Moreno; Glenn C Telling
Journal:  Cold Spring Harb Perspect Med       Date:  2018-06-01       Impact factor: 6.915

2.  A dual fluorescent multiprobe assay for prion protein genotyping in sheep.

Authors:  Mario Van Poucke; Jo Vandesompele; Marc Mattheeuws; Alex Van Zeveren; Luc J Peelman
Journal:  BMC Infect Dis       Date:  2005-03-15       Impact factor: 3.090

3.  Trends in genotype frequency resulting from breeding for resistance to classical scrapie in Belgium (2006 ˜ 2011).

Authors:  Alexandre Dobly; Sara Van der Heyden; Stefan Roels
Journal:  J Vet Sci       Date:  2013-02-05       Impact factor: 1.672

4.  A descriptive study of the prevalence of atypical and classical scrapie in sheep in 20 European countries.

Authors:  Alexandre Fediaevsky; Sue C Tongue; Maria Nöremark; Didier Calavas; Giuseppe Ru; Petter Hopp
Journal:  BMC Vet Res       Date:  2008-06-10       Impact factor: 2.741
  4 in total

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