Literature DB >> 15070295

Highly enantioselective addition of phenylacetylene to aldehydes catalyzed by a camphorsulfonamide ligand.

Zhaoqing Xu1, Chao Chen, Jiangke Xu, Mingbo Miao, Wenjin Yan, Rui Wang.   

Abstract

The asymmetric addition of phenylacetylene to aldehydes was carried out by using a camphorsulfonamide titanium complex as a catalyst. The reactions proceeded under mild conditions and gave the products with good yields and high ees. This system is very useful for the synthesis of chiral propargylic alcohol. [reaction: see text]

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Year:  2004        PMID: 15070295     DOI: 10.1021/ol036418u

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  3 in total

1.  Dinuclear Zn-catalyzed asymmetric alkynylation of unsaturated aldehydes.

Authors:  Barry M Trost; Andrew H Weiss; Axel Jacobi von Wangelin
Journal:  J Am Chem Soc       Date:  2006-01-11       Impact factor: 15.419

2.  1,1'-Binaphthyl Ligands with Bulky 3,3'-Tertiaryalkyl Substituents for the Asymmetric Alkyne Addition to Aromatic Aldehydes.

Authors:  Qin Wang; Shan-Yong Chen; Xiao-Qi Yu; Lin Pu
Journal:  Tetrahedron       Date:  2007-05-21       Impact factor: 2.457

3.  Highly enantioselective addition of phenylethynylzinc to aldehydes catalyzed by chiral cyclopropane-based amino alcohols.

Authors:  Bing Zheng; Zhiyuan Li; Feipeng Liu; Yanhua Wu; Junjian Shen; Qinghua Bian; Shicong Hou; Ming Wang
Journal:  Molecules       Date:  2013-12-11       Impact factor: 4.411

  3 in total

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