Literature DB >> 15070241

Dosimetry of a prototype retractable eMLC for fixed-beam electron therapy.

Kenneth R Hogstrom1, Robert A Boyd, John A Antolak, Michelle M Svatos, Bruce A Faddegon, Julian G Rosenman.   

Abstract

An electron multileaf collimator (eMLC) has been designed that is unique in that it retracts to 37 cm from the isocenter [63-cm source-to-collimator distance (SCD)] and can be deployed to distances of 20 and 10 cm from the isocenter (80 and 90 cm SCD, respectively). It is expected to be capable of arc therapy at 63 cm SCD; isocentric, fixed-beam therapy at 80 cm SCD; and source-to-surface distance (SSD), fixed-beam therapy at 90 cm SCD. In all positions, its leaves could be used for unmodulated or intensity-modulated therapy. Our goal in the present work is to describe the general characteristics of the eMLC and to demonstrate that its leakage characteristics and dosimetry are adequate for SSD, fixed-beam therapy as an alternative to Cerrobend cutouts with applicators once the prototype's leaves are motorized. Our eMLC data showed interleaf electron leakage at 15 MeV to be less than 0.1% based on a 0.0025 cm manufacturing tolerance, and lateral electron leakage at 5 and 15 MeV to be less than 2%. X-ray leakage through the leaves was 1.6% at 15 MeV. Our data showed that beam penumbra was independent of direction and leaf position. The dosimetric properties of square fields formed by the eMLC were very consistent with those formed by Cerrobend inserts in the 20 x 20 cm2 applicator. Output factors exhibited similar field-size dependence. Airgap factors exhibited almost identical field-size dependence at two SSDs (105 and 110 cm), consistent with the common assumption that airgap factors are applicator independent. Percent depth-dose curves were similar, but showed variations up to 3% in the buildup region. The pencil-beam algorithm (PBA) fit measured data from the eMLC and applicator-cutout systems equally well, and the resulting two-dimensional (2-D) dose distributions, as predicted by the PBA, agreed well at common airgap distance. Simulating patient setups for breast and head and neck treatments showed that almost all fields could be treated using similar SSDs as when using applicators, although head and neck treatments require placing the patient's head on a head-holder treatment table extension. The results of this work confirmed our design goals and support the potential use of the eMLC design in the clinical setting. The eMLC should allow the same treatments as are typically delivered with the electron applicator-cutout system currently used for fixed-beam therapy.

Entities:  

Mesh:

Year:  2004        PMID: 15070241     DOI: 10.1118/1.1644516

Source DB:  PubMed          Journal:  Med Phys        ISSN: 0094-2405            Impact factor:   4.071


  15 in total

1.  Optimization of dual electron multileaf collimator materials by use of EGSnrc.

Authors:  Samuel O Inyang; Alan C Chamberlain
Journal:  Radiol Phys Technol       Date:  2010-05-13

2.  Monte Carlo simulations of electron beams collimated with a dual electron multileaf collimator: a feasibility study.

Authors:  S O Inyang; A C Chamberlain
Journal:  Radiol Phys Technol       Date:  2009-07-04

3.  Preliminary comparison of helical tomotherapy and mixed beams of unmodulated electrons and intensity modulated radiation therapy for treating superficial cancers of the parotid gland and nasal cavity.

Authors:  Olivier Blasi; Jonas D Fontenot; Robert S Fields; John P Gibbons; Kenneth R Hogstrom
Journal:  Radiat Oncol       Date:  2011-12-28       Impact factor: 3.481

4.  Electron modulated arc therapy (EMAT) using photon MLC for postmastectomy chest wall treatment I: Monte Carlo-based dosimetric characterizations.

Authors:  Chaoqiong Ma; David Parsons; Mingli Chen; Steve Jiang; Qing Hou; Xuejun Gu; Weiguo Lu
Journal:  Phys Med       Date:  2019-10-10       Impact factor: 2.685

5.  The accuracy of EGSnrc, Geant4 and PENELOPE Monte Carlo systems for the simulation of electron scatter in external beam radiotherapy.

Authors:  Bruce A Faddegon; Iwan Kawrakow; Yuri Kubyshin; Joseph Perl; Josep Sempau; Laszlo Urban
Journal:  Phys Med Biol       Date:  2009-09-24       Impact factor: 3.609

6.  Design and evaluation of electron beam energy degraders for breast boost irradiation.

Authors:  Jong In Park; Sung Whan Ha; Jung-In Kim; Hyunseok Lee; Jaegi Lee; Il Han Kim; Sung-Joon Ye
Journal:  Radiat Oncol       Date:  2016-08-31       Impact factor: 3.481

7.  Image-guided bolus electron conformal therapy - a case study.

Authors:  Omar A Zeidan; Bhavin D Chauhan; William W Estabrook; Twyla R Willoughby; Rafael R Manon; Sanford L Meeks
Journal:  J Appl Clin Med Phys       Date:  2010-10-07       Impact factor: 2.102

8.  Introduction to passive electron intensity modulation.

Authors:  Kenneth R Hogstrom; Robert L Carver; Erin L Chambers; Kevin Erhart
Journal:  J Appl Clin Med Phys       Date:  2017-09-06       Impact factor: 2.102

9.  Dosimetric characteristics of an electron multileaf collimator for modulated electron radiation therapy.

Authors:  Ahmed Abdel Rahman Eldib; Mohamed I ElGohary; Jiajin Fan; Lihui Jin; Jinsheng Li; Charlie Ma; Nader A Elsherbini
Journal:  J Appl Clin Med Phys       Date:  2010-04-12       Impact factor: 2.102

10.  Measurement and Monte Carlo simulation for energy- and intensity-modulated electron radiotherapy delivered by a computer-controlled electron multileaf collimator.

Authors:  Lihui Jin; Ahmed Eldib; Jinsheng Li; Ismail Emam; Jiajin Fan; Lu Wang; C-M Ma
Journal:  J Appl Clin Med Phys       Date:  2014-01-06       Impact factor: 2.102

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.