PURPOSE OF REVIEW: This article provides an overview of randomized studies of altered fractionated radiotherapy (RT) in Head and Neck squamous cell carcinoma. RECENT FINDINGS: Both hyperfractionated RT and accelerated RT may improve tumor control probability as compared to conventional RT, along with increased but manageable toxicity and a modest improvement in survival. SUMMARY: Altered RT is a tool that can improve the results obtained with conventional RT in Head and squamous cell carcinoma.
PURPOSE OF REVIEW: This article provides an overview of randomized studies of altered fractionated radiotherapy (RT) in Head and Neck squamous cell carcinoma. RECENT FINDINGS: Both hyperfractionated RT and accelerated RT may improve tumor control probability as compared to conventional RT, along with increased but manageable toxicity and a modest improvement in survival. SUMMARY: Altered RT is a tool that can improve the results obtained with conventional RT in Head and squamous cell carcinoma.