Literature DB >> 15068820

Generally recognized as safe (GRAS): history and description.

George A Burdock1, Ioana G Carabin.   

Abstract

Generally recognized as safe (GRAS), a system for review and approval of ingredients for addition to food, was conceived at a time when the need for a less doctrinaire review of food ingredients was critical. The GRAS approval process for a food ingredient relies on the judgment of "...experts qualified by scientific training and experience to evaluate its safety..." the end product of which is no better or worse than that by FDA, but often more expeditious. The process and requirements for a successful GRAS determination are discussed and compared with that of the food additive petition (FAP) process. The future of the GRAS process is assured by its history of successful performance, bringing safe food ingredients to the consumer in a timely manner.

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Year:  2004        PMID: 15068820     DOI: 10.1016/j.toxlet.2003.07.004

Source DB:  PubMed          Journal:  Toxicol Lett        ISSN: 0378-4274            Impact factor:   4.372


  21 in total

1.  Development of a novel cup cake with unique properties of essential oil of betel leaf (Piper betle L.) for sustainable entrepreneurship.

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Journal:  J Food Sci Technol       Date:  2014-09-17       Impact factor: 2.701

2.  Developmental toxicity assessment of common excipients using a stem cell-based in vitro morphogenesis model.

Authors:  Chloe J Yuan; Yusuke Marikawa
Journal:  Food Chem Toxicol       Date:  2017-09-18       Impact factor: 6.023

Review 3.  Current Status of Supersaturable Self-Emulsifying Drug Delivery Systems.

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Journal:  Pharmaceutics       Date:  2020-04-16       Impact factor: 6.321

Review 4.  Polysaccharide-Based Controlled Release Systems for Therapeutics Delivery and Tissue Engineering: From Bench to Bedside.

Authors:  Tianxin Miao; Junqing Wang; Yun Zeng; Gang Liu; Xiaoyuan Chen
Journal:  Adv Sci (Weinh)       Date:  2018-01-08       Impact factor: 16.806

5.  The role of regulated clinical trials in the development of bacteriophage therapeutics.

Authors:  Helena Mrt Parracho; Ben H Burrowes; Mark C Enright; Malcolm L McConville; David R Harper
Journal:  J Mol Genet Med       Date:  2012-04-23

6.  Chemoinformatic analysis of GRAS (Generally Recognized as Safe) flavor chemicals and natural products.

Authors:  José L Medina-Franco; Karina Martínez-Mayorga; Terry L Peppard; Alberto Del Rio
Journal:  PLoS One       Date:  2012-11-30       Impact factor: 3.240

7.  Rectal microbicides: clinically relevant approach to the design of rectal specific placebo formulations.

Authors:  Lin Wang; Roger L Schnaare; Charlene Dezzutti; Peter A Anton; Lisa C Rohan
Journal:  AIDS Res Ther       Date:  2011-03-07       Impact factor: 2.250

8.  Thymoquinone-loaded nanostructured lipid carrier exhibited cytotoxicity towards breast cancer cell lines (MDA-MB-231 and MCF-7) and cervical cancer cell lines (HeLa and SiHa).

Authors:  Wei Keat Ng; Latifah Saiful Yazan; Li Hua Yap; Wan Abd Ghani Wan Nor Hafiza; Chee Wun How; Rasedee Abdullah
Journal:  Biomed Res Int       Date:  2015-01-06       Impact factor: 3.411

9.  Display of multimeric antimicrobial peptides on the Escherichia coli cell surface and its application as whole-cell antibiotics.

Authors:  Ju Ri Shin; Ki Jung Lim; Da Jung Kim; Ju Hyun Cho; Sun Chang Kim
Journal:  PLoS One       Date:  2013-03-14       Impact factor: 3.240

10.  D-Allulose Production from D-Fructose by Permeabilized Recombinant Cells of Corynebacterium glutamicum Cells Expressing D-Allulose 3-Epimerase Flavonifractor plautii.

Authors:  Chul-Soon Park; Taeyong Kim; Seung-Hye Hong; Kyung-Chul Shin; Kyoung-Rok Kim; Deok-Kun Oh
Journal:  PLoS One       Date:  2016-07-28       Impact factor: 3.240

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