| Literature DB >> 15068460 |
Amy Stanway1, Marius Rademaker, Paul Newman.
Abstract
A 55-year-old woman with severe, chronic, treatment-resistant ulcerating necrobiosis lipoidica of the shins was commenced on oral cyclosporin at a dose of 2.5 mg/kg/day. Improvement started within 1 week of commencing treatment, and the lesions healed completely over 8 months. Further ulceration occurred 3 months after discontinuing cyclosporin, with improvement on reintroduction of cyclosporin. There have been four previous case reports of healing of treatment-resistant ulcerating necrobiosis lipoidica with cyclosporin.Entities:
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Year: 2004 PMID： 15068460 DOI： 10.1111/j.1440-0960.2004.00059.x
Source DB: PubMed Journal: Australas J Dermatol ISSN： 0004-8380 Impact factor: 2.875