Literature DB >> 15067312

The immune response to AIDS virus infection: good, bad, or both?

Steven G Deeks1, Bruce D Walker.   

Abstract

A potent antigen-specific T cell response to HIV infection can contribute to the control of viral replication and is therefore beneficial to the host. However, HIV-mediated increases in generalized T cell activation also appear to accelerate both viral replication and CD4+ T cell depletion. A new study in the JCI attempts to experimentally distinguish the beneficial versus harmful aspects of this immune response.

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Year:  2004        PMID： 15067312      PMCID： PMC362127          DOI： 10.1172/JCI21318

Source DB:  PubMed          Journal:  J Clin Invest        ISSN： 0021-9738            Impact factor:   14.808


  18 in total

1.  Gradual adaptation of HIV to human host populations: good or bad news?

Authors:  Christian Brander; Bruce D Walker
Journal:  Nat Med       Date:  2003-11       Impact factor: 53.440

2.  Simian immunodeficiency virus replicates to high levels in sooty mangabeys without inducing disease.

Authors:  M A Rey-Cuillé; J L Berthier; M C Bomsel-Demontoy; Y Chaduc; L Montagnier; A G Hovanessian; L A Chakrabarti
Journal:  J Virol       Date:  1998-05       Impact factor: 5.103

3.  Normal T-cell turnover in sooty mangabeys harboring active simian immunodeficiency virus infection.

Authors:  L A Chakrabarti; S R Lewin; L Zhang; A Gettie; A Luckay; L N Martin; E Skulsky; D D Ho; C Cheng-Mayer; P A Marx
Journal:  J Virol       Date:  2000-02       Impact factor: 5.103

4.  Simian immunodeficiency virus replicates to high levels in naturally infected African green monkeys without inducing immunologic or neurologic disease.

Authors:  S R Broussard; S I Staprans; R White; E M Whitehead; M B Feinberg; J S Allan
Journal:  J Virol       Date:  2001-03       Impact factor: 5.103

5.  Evolution and transmission of stable CTL escape mutations in HIV infection.

Authors:  P J Goulder; C Brander; Y Tang; C Tremblay; R A Colbert; M M Addo; E S Rosenberg; T Nguyen; R Allen; A Trocha; M Altfeld; S He; M Bunce; R Funkhouser; S I Pelton; S K Burchett; K McIntosh; B T Korber; B D Walker
Journal:  Nature       Date:  2001-07-19       Impact factor: 49.962

6.  Subpopulations of long-lived and short-lived T cells in advanced HIV-1 infection.

Authors:  Marc K Hellerstein; Rebecca A Hoh; Mary Beth Hanley; Denise Cesar; Daniel Lee; Richard A Neese; Joseph M McCune
Journal:  J Clin Invest       Date:  2003-09       Impact factor: 14.808

7.  Turnover of lymphocytes and conceptual paradigms in HIV infection.

Authors:  Guido Silvestri; Mark B Feinberg
Journal:  J Clin Invest       Date:  2003-09       Impact factor: 14.808

8.  CD8+ T-lymphocyte activation in HIV-1 disease reflects an aspect of pathogenesis distinct from viral burden and immunodeficiency.

Authors:  Z Liu; W G Cumberland; L E Hultin; A H Kaplan; R Detels; J V Giorgi
Journal:  J Acquir Immune Defic Syndr Hum Retrovirol       Date:  1998-08-01

9.  Strong cell-mediated immune responses are associated with the maintenance of low-level viremia in antiretroviral-treated individuals with drug-resistant human immunodeficiency virus type 1.

Authors:  Steven G Deeks; Jeffrey N Martin; Elizabeth Sinclair; Jeff Harris; Torsten B Neilands; Holden T Maecker; Elilta Hagos; Terri Wrin; Christos J Petropoulos; Barry Bredt; Joseph M McCune
Journal:  J Infect Dis       Date:  2004-01-07       Impact factor: 5.226

10.  Blockade of T cell costimulation reveals interrelated actions of CD4+ and CD8+ T cells in control of SIV replication.

Authors:  David A Garber; Guido Silvestri; Ashley P Barry; Andrew Fedanov; Natalia Kozyr; Harold McClure; David C Montefiori; Christian P Larsen; John D Altman; Silvija I Staprans; Mark B Feinberg
Journal:  J Clin Invest       Date:  2004-03       Impact factor: 14.808
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  31 in total

1.  Preservation HIV-1-specific IFNγ+ CD4+ T-cell responses in breakthrough infections after exposure to tenofovir gel in the CAPRISA 004 microbicide trial.

Authors:  Marianne W Mureithi; Danielle Poole; Vivek Naranbhai; Shabashini Reddy; Nompumelelo P Mkhwanazi; Sengeziwe Sibeko; Lise Werner; Quarraisha Abdool Karim; Salim Abdool Karim; Thumbi Ndung'u; Marcus Altfeld
Journal:  J Acquir Immune Defic Syndr       Date:  2012-06-01       Impact factor: 3.731

2.  Changes in human immunodeficiency virus type 1 fitness and genetic diversity during disease progression.

Authors:  Ryan M Troyer; Kalonji R Collins; Awet Abraha; Erika Fraundorf; Dawn M Moore; Randall W Krizan; Zahra Toossi; Robert L Colebunders; Mark A Jensen; James I Mullins; Guido Vanham; Eric J Arts
Journal:  J Virol       Date:  2005-07       Impact factor: 5.103

3.  Syndecan-Fc hybrid molecule as a potent in vitro microbicidal anti-HIV-1 agent.

Authors:  Michael D Bobardt; Udayan Chatterji; Lana Schaffer; Lot de Witte; Philippe A Gallay
Journal:  Antimicrob Agents Chemother       Date:  2010-05-03       Impact factor: 5.191

4.  Personal and Clinical Vaginal Lubricants: Impact on Local Vaginal Microenvironment and Implications for Epithelial Cell Host Response and Barrier Function.

Authors:  Ellen M Wilkinson; Paweł Łaniewski; Melissa M Herbst-Kralovetz; Rebecca M Brotman
Journal:  J Infect Dis       Date:  2019-11-06       Impact factor: 5.226

5.  2B4 expression on natural killer cells increases in HIV-1 infected patients followed prospectively during highly active antiretroviral therapy.

Authors:  S R Ostrowski; H Ullum; B K Pedersen; J Gerstoft; T L Katzenstein
Journal:  Clin Exp Immunol       Date:  2005-09       Impact factor: 4.330

6.  Unique pathology in simian immunodeficiency virus-infected rapid progressor macaques is consistent with a pathogenesis distinct from that of classical AIDS.

Authors:  Charles R Brown; Meggan Czapiga; Juraj Kabat; Que Dang; Ilnour Ourmanov; Yoshiaki Nishimura; Malcolm A Martin; Vanessa M Hirsch
Journal:  J Virol       Date:  2007-03-21       Impact factor: 5.103

7.  Divergent host responses during primary simian immunodeficiency virus SIVsm infection of natural sooty mangabey and nonnatural rhesus macaque hosts.

Authors:  Guido Silvestri; Andrew Fedanov; Stephanie Germon; Natalia Kozyr; William J Kaiser; David A Garber; Harold McClure; Mark B Feinberg; Silvija I Staprans
Journal:  J Virol       Date:  2005-04       Impact factor: 5.103

8.  Inflammation and Fibrosis in HIV: Getting to the Heart of the Matter.

Authors:  Priscilla Y Hsue; Ahmed Tawakol
Journal:  Circ Cardiovasc Imaging       Date:  2016-03       Impact factor: 7.792

Review 9.  Mucosal immunology of HIV infection.

Authors:  Huanbin Xu; Xiaolei Wang; Ronald S Veazey
Journal:  Immunol Rev       Date:  2013-07       Impact factor: 12.988

10.  Increased T-cell activation and Th1 cytokine concentrations prior to the diagnosis of B-cell lymphoma in HIV infected patients.

Authors:  David Eric Ouedraogo; Alain Makinson; Nils Kuster; Nicolas Nagot; Pierre-Alain Rubbo; Karine Bollore; Vincent Foulongne; Guillaume Cartron; Daniel Olive; Jacques Reynes; Jean-Pierre Vendrell; Edouard Tuaillon
Journal:  J Clin Immunol       Date:  2012-08-23       Impact factor: 8.317
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