Literature DB >> 15066739

Dermal absorption of isopropyl alcohol from a commercial hand rub: implications for its use in hand decontamination.

P Turner1, B Saeed, M C Kelsey.   

Abstract

Isopropyl alcohol-containing hand rubs are widely used in healthcare for hand decontamination. Ten healthy adult volunteers applied a commercially available isopropyl alcohol-containing hand rub to their hands every 10 min over a 4 h period. Blood isopropyl alcohol levels were measured at the beginning and end of the study. At the end of the study, measurable blood isopropyl alcohol levels (range 0.5-1.8 mg/l) were recorded in nine subjects. We confirmed that isopropyl alcohol could be absorbed through the intact skin of adult humans. The social and medical implications are discussed.

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Year:  2004        PMID: 15066739     DOI: 10.1016/j.jhin.2004.01.005

Source DB:  PubMed          Journal:  J Hosp Infect        ISSN: 0195-6701            Impact factor:   3.926


  7 in total

1.  Can alcohol-based hand-rub solutions cause you to lose your driver's license? Comparative cutaneous absorption of various alcohols.

Authors:  T L Brown; S Gamon; P Tester; R Martin; K Hosking; G C Bowkett; D Gerostamoulos; M L Grayson
Journal:  Antimicrob Agents Chemother       Date:  2006-12-28       Impact factor: 5.191

2.  Transdermal absorption of ethanol- and 1-propanol-containing hand disinfectants.

Authors:  Reinhold Andreas Lang; Dianne Egli-Gany; Florian Holger Hubert Brill; Johannes Georg Böttrich; Marion Breuer; Burkhard Breuer; Martin Hartwig Kirschner
Journal:  Langenbecks Arch Surg       Date:  2010-12-01       Impact factor: 3.445

3.  Transdermal resorption of an ethanol- and 2-propanol-containing skin disinfectant.

Authors:  Martin Hartwig Kirschner; Reinhold Andreas Lang; Burkhard Breuer; Marion Breuer; Corinna Schulze Gronover; Thomas Zwingers; Johannes Georg Böttrich; Andreas Arndt; Ute Brauer; Matthias Hintzpeter; Marc-Alexander Burmeister; Jan-Dirk Fauteck
Journal:  Langenbecks Arch Surg       Date:  2007-11-08       Impact factor: 3.445

4.  The alcohol used for cleansing the venipuncture site does not jeopardize blood and plasma alcohol measurement with head-space gas chromatography and an enzymatic assay.

Authors:  Giuseppe Lippi; Ana-Maria Simundic; Giacomo Musile; Elisa Danese; Gianluca Salvagno; Franco Tagliaro
Journal:  Biochem Med (Zagreb)       Date:  2017-06-15       Impact factor: 2.313

5.  Potential methanol toxicity and the importance of using a standardised alcohol-based hand rub formulation in the era of COVID-19.

Authors:  K Dear; L Grayson; R Nixon
Journal:  Antimicrob Resist Infect Control       Date:  2020-08-08       Impact factor: 4.887

6.  Religion and culture: potential undercurrents influencing hand hygiene promotion in health care.

Authors:  Benedetta Allegranzi; Ziad A Memish; Liam Donaldson; Didier Pittet
Journal:  Am J Infect Control       Date:  2008-10-03       Impact factor: 2.918

Review 7.  Sensitivity of SARS-CoV-2 towards Alcohols: Potential for Alcohol-Related Toxicity in Humans.

Authors:  Debasish Basak; Subrata Deb
Journal:  Life (Basel)       Date:  2021-12-03
  7 in total

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