Purohit Ashok1, Bhagat Meenakshi. 1. Department of Zoology, JNV University, Jodhpur (Raj.) 342 005, India. purohit1411@yahoo.com
Abstract
AIM: To study the contraceptive effect of the crude extracts of Curcuma longa in male albino rats. METHODS: Rats were fed orally with Curcuma longa aqueous and 70% alcoholic extract for 60 days (500 mg x kg(-1) x day(-1)). RESULTS: A reduction in sperm motility and density was observed in both the treated groups. CONCLUSION: Curcuma longa may have affected the androgen synthesis either by inhibiting the Leydig cell function or the hypothalamus pituitary axis and as a result, spermatogenesis is arrested.
AIM: To study the contraceptive effect of the crude extracts of Curcuma longa in male albino rats. METHODS:Rats were fed orally with Curcuma longa aqueous and 70% alcoholic extract for 60 days (500 mg x kg(-1) x day(-1)). RESULTS: A reduction in sperm motility and density was observed in both the treated groups. CONCLUSION:Curcuma longa may have affected the androgen synthesis either by inhibiting the Leydig cell function or the hypothalamus pituitary axis and as a result, spermatogenesis is arrested.
Authors: Lubov V Krepkova; Valentina V Bortnikova; Aleksandra N Babenko; Praskovya G Mizina; Vladimir A Mkhitarov; Kathleen M Job; Catherine M Sherwin; Elena Y Enioutina Journal: BMC Complement Med Ther Date: 2021-01-13