A Meyer1, U Niemann, M Behrend. 1. Abt. Strahlentherapie, Med. Hochschule, Hannover, Carl-Neuberg-Str. 1, 30625 Hannover, Germany.
Abstract
UNLABELLED: We report on a series of 20 consecutive patients (10 males, 10 females) with adrenal cortical carcinoma (ACC) who were treated by surgery between 1987 and 2001. AIM: The aim of this study was to evaluate the outcome and the role of surgery in the management of this tumour. RESULT: One patient was at stage I, five patients at stage II, five patients at stage III and nine patients at stage IV of disease. Ten patients suffered from a functioning tumour, whilst ten patients revealed non-functioning tumours. In all patients a transabdominal approach was performed for the complete resection of the tumour, adjacent organs or metastases. The medium survival after surgical resection, calculated by the Kaplan-Meier method, was 45 months for the overall group, 65 months for patients at stage I or II, 38 months for patients at stage III and 19 months for patients at stage IV of disease. The 5-year survival rate for all patients was 23%, for patients at stage I or II 33%, for patients at stage III 20%, and for patients at stage IV around zero. CONCLUSION: Radical surgery with a complete resection of the tumour, adjacent organs, solitary metastases and loco-regional recurrence wherever possible improves survival, even at advanced stages of disease.
UNLABELLED: We report on a series of 20 consecutive patients (10 males, 10 females) with adrenal cortical carcinoma (ACC) who were treated by surgery between 1987 and 2001. AIM: The aim of this study was to evaluate the outcome and the role of surgery in the management of this tumour. RESULT: One patient was at stage I, five patients at stage II, five patients at stage III and nine patients at stage IV of disease. Ten patients suffered from a functioning tumour, whilst ten patients revealed non-functioning tumours. In all patients a transabdominal approach was performed for the complete resection of the tumour, adjacent organs or metastases. The medium survival after surgical resection, calculated by the Kaplan-Meier method, was 45 months for the overall group, 65 months for patients at stage I or II, 38 months for patients at stage III and 19 months for patients at stage IV of disease. The 5-year survival rate for all patients was 23%, for patients at stage I or II 33%, for patients at stage III 20%, and for patients at stage IV around zero. CONCLUSION: Radical surgery with a complete resection of the tumour, adjacent organs, solitary metastases and loco-regional recurrence wherever possible improves survival, even at advanced stages of disease.
Authors: Maria J Monroy-Iglesias; Sonpreet Rai; Francesco A Mistretta; Graham Roberts; Harvey Dickinson; Beth Russell; Charlotte Moss; Rita De Berardinis; Matteo Ferro; Gennaro Musi; Christian Brown; Rajesh Nair; Ramesh Thurairaja; Archana Fernando; Paul Cathcart; Azhar Khan; Prokar Dasgupta; Sachin Malde; Marios Hadijpavlou; Saoirse Dolly; Kate Haire; Marta Tagliabue; Ottavio de Cobelli; Ben Challacombe; Mieke Van Hemelrijck Journal: BJUI Compass Date: 2022-01-27
Authors: Brian C Gulack; Kristy L Rialon; Brian R Englum; Jina Kim; Lindsay J Talbot; Obinna O Adibe; Henry E Rice; Elisabeth T Tracy Journal: J Pediatr Surg Date: 2015-10-23 Impact factor: 2.545