Literature DB >> 15063893

Surgical treatment of liver metastases by radiofrequency ablation, resection, or in combination.

S Evrard1, Y Becouarn, M Fonck, R Brunet, S Mathoulin-Pelissier, V Picot.   

Abstract

AIMS: Radiofrequency ablation (RFA) has a role in the treatment of unresectable liver metastases either percutaneously or in open surgery. The aim of this study was to determine the feasibility and value using RFA, resection or in combination to cure liver metastases of colorectal or other origin.
METHODS: Fifty-two consecutive patients were operated on with the intention to treat their liver metastases using both techniques of RFA and resection in the same curative intent. A CT scan was performed 2 months postoperatively and then every 4 months.
RESULTS: Fifty patients with 137 metastases could be treated: 55 lesions were resected and 82 were ablated. Curative treatment of 13 patients could only be achieved by using RFA combined with resection. Morbidity was 16% and local treatment proved insufficient in three cases. Estimated 1-year survival probabilities were, respectively, 0.85 in the colorectal group and 0.80 in the non-colorectal group.
CONCLUSIONS: RFA increased resectability of liver metastases and reduced the morbidity. Respective indications of both techniques were complementary and depend on the size and the topography of the lesion to be treated.

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Year:  2004        PMID: 15063893     DOI: 10.1016/j.ejso.2004.01.019

Source DB:  PubMed          Journal:  Eur J Surg Oncol        ISSN: 0748-7983            Impact factor:   4.424


  19 in total

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6.  Therapeutic efficacy of combined intraoperative ablation and resection for colorectal liver metastases: an international, multi-institutional analysis.

Authors:  Mechteld C de Jong; Mark G van Vledder; Dario Ribero; Catherine Hubert; Jean-François Gigot; Michael A Choti; Richard D Schulick; Lorenzo Capussotti; Cornelis H Dejong; Timothy M Pawlik
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