Literature DB >> 15063847

Mfd, the bacterial transcription repair coupling factor: translocation, repair and termination.

Jeffrey Roberts1, Joo-Seop Park.   

Abstract

Mfd is a widely conserved bacterial protein that couples DNA repair with transcription. Mfd recognizes RNA polymerase stalled at a non-coding template site of DNA damage, disrupts the transcription complex to release the transcript and enzyme, and recruits the DNA excision repair machinery to the site. The mechanism of RNA release has been illuminated by the discovery that Mfd causes forward translocation of RNA polymerase, using an ATP-dependent motor that is highly homologous to that of the Holliday branch migration protein RecG.

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Year:  2004        PMID： 15063847     DOI： 10.1016/j.mib.2004.02.014

Source DB:  PubMed          Journal:  Curr Opin Microbiol        ISSN： 1369-5274            Impact factor:   7.934


  38 in total

1.  Transcriptional de-repression and Mfd are mutagenic in stressed Bacillus subtilis cells.

Authors:  Holly Anne Martin; Mario Pedraza-Reyes; Ronald E Yasbin; Eduardo A Robleto
Journal:  J Mol Microbiol Biotechnol       Date:  2012-01-13

2.  Nucleotide excision repair (NER) machinery recruitment by the transcription-repair coupling factor involves unmasking of a conserved intramolecular interface.

Authors:  Alexandra M Deaconescu; Anastasia Sevostyanova; Irina Artsimovitch; Nikolaus Grigorieff
Journal:  Proc Natl Acad Sci U S A       Date:  2012-02-13       Impact factor: 11.205

3.  Importance of the tmRNA system for cell survival when transcription is blocked by DNA-protein cross-links.

Authors:  H Kenny Kuo; Rachel Krasich; Ashok S Bhagwat; Kenneth N Kreuzer
Journal:  Mol Microbiol       Date:  2010-09-16       Impact factor: 3.501

Review 4.  What happens when replication and transcription complexes collide?

Authors:  Richard T Pomerantz; Mike O'Donnell
Journal:  Cell Cycle       Date:  2010-07-01       Impact factor: 4.534

Review 5.  RNA polymerase between lesion bypass and DNA repair.

Authors:  Alexandra M Deaconescu
Journal:  Cell Mol Life Sci       Date:  2013-06-27       Impact factor: 9.261

6.  Allosteric Activation of Bacterial Swi2/Snf2 (Switch/Sucrose Non-fermentable) Protein RapA by RNA Polymerase: BIOCHEMICAL AND STRUCTURAL STUDIES.

Authors:  Smita Kakar; Xianyang Fang; Lucyna Lubkowska; Yan Ning Zhou; Gary X Shaw; Yun-Xing Wang; Ding Jun Jin; Mikhail Kashlev; Xinhua Ji
Journal:  J Biol Chem       Date:  2015-08-13       Impact factor: 5.157

7.  Role of forward translocation in nucleoside triphosphate phosphohydrolase I (NPH I)-mediated transcription termination of vaccinia virus early genes.

Authors:  Jessica Tate; Paul Gollnick
Journal:  J Biol Chem       Date:  2011-11-07       Impact factor: 5.157

Review 8.  Transcriptional interference--a crash course.

Authors:  Keith E Shearwin; Benjamin P Callen; J Barry Egan
Journal:  Trends Genet       Date:  2005-06       Impact factor: 11.639

9.  Role of DNA bubble rewinding in enzymatic transcription termination.

Authors:  Joo-Seop Park; Jeffrey W Roberts
Journal:  Proc Natl Acad Sci U S A       Date:  2006-03-21       Impact factor: 11.205

Review 10.  Molecular traffic jams on DNA.

Authors:  Ilya J Finkelstein; Eric C Greene
Journal:  Annu Rev Biophys       Date:  2013-02-28       Impact factor: 12.981
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