| Literature DB >> 15062124 |
Annabelle Lewis1, Adele Murrell.
Abstract
The DNA-binding protein CTCF, which acts as a chromatin 'insulator', regulates imprinting of the mammalian Igf2 and H19 genes in a methylation-sensitive manner. It has now been shown that CTCF is also required for protection against de novo methylation of the differentially methylated domain of H19 in the female germline.Entities:
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Year: 2004 PMID: 15062124 DOI: 10.1016/j.cub.2004.03.026
Source DB: PubMed Journal: Curr Biol ISSN: 0960-9822 Impact factor: 10.834