Literature DB >> 15061872

Herpetic eye disease: immunopathogenesis and therapeutic measures.

Shilpa Deshpande1, Kaustuv Banerjee, Partha Sarathi Biswas, Barry T Rouse.   

Abstract

Infection of the cornea with herpes simplex virus (HSV) can result in a chronic disease called herpetic stromal keratitis (HSK). The disease represents one of the leading causes of infectious blindness in the Western world. Immune-mediated cellular damage is suspected in the pathogenesis of human HSK. The murine model has been pivotal in further establishing HSK as an immunopathological disease. This article reviews understanding of HSK, both in humans and in the mouse model, with an emphasis on possible future therapeutic strategies to counteract this blinding immunoinflammatory disease.

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Year:  2004        PMID： 15061872     DOI： 10.1017/S1462399404007604

Source DB:  PubMed          Journal:  Expert Rev Mol Med        ISSN： 1462-3994            Impact factor:   5.600


  23 in total

1.  Controlling herpes simplex virus-induced ocular inflammatory lesions with the lipid-derived mediator resolvin E1.

Authors:  Naveen K Rajasagi; Pradeep B J Reddy; Amol Suryawanshi; Sachin Mulik; Per Gjorstrup; Barry T Rouse
Journal:  J Immunol       Date:  2010-12-27       Impact factor: 5.422

Review 2.  Herpesvirus Entry Mediator and Ocular Herpesvirus Infection: More than Meets the Eye.

Authors:  Rebecca G Edwards; Richard Longnecker
Journal:  J Virol       Date:  2017-06-09       Impact factor: 5.103

3.  Innate recognition network driving herpes simplex virus-induced corneal immunopathology: role of the toll pathway in early inflammatory events in stromal keratitis.

Authors:  Pranita P Sarangi; Bumseok Kim; Evelyn Kurt-Jones; Barry T Rouse
Journal:  J Virol       Date:  2007-08-08       Impact factor: 5.103

Review 4.  Pathogenesis of herpes simplex keratitis: The host cell response and ocular surface sequelae to infection and inflammation.

Authors:  Ann-Marie Lobo; Alex M Agelidis; Deepak Shukla
Journal:  Ocul Surf       Date:  2018-10-11       Impact factor: 5.033

Review 5.  Application of our understanding of pathogenesis of herpetic stromal keratitis for novel therapy.

Authors:  Naveen K Rajasagi; Barry T Rouse
Journal:  Microbes Infect       Date:  2018-01-09       Impact factor: 2.700

6.  Substance P in the corneal stroma regulates the severity of herpetic stromal keratitis lesions.

Authors:  Brandon S Twardy; Rudragouda Channappanavar; Susmit Suvas
Journal:  Invest Ophthalmol Vis Sci       Date:  2011-11-04       Impact factor: 4.799

7.  Controlling herpetic stromal keratitis by modulating lymphotoxin-alpha-mediated inflammatory pathways.

Authors:  Tamara Veiga-Parga; Fernanda Giménez; Sachin Mulik; Eugene Y Chiang; Jane L Grogan; Barry T Rouse
Journal:  Microbes Infect       Date:  2013-07-10       Impact factor: 2.700

8.  Sculpting MHC class II-restricted self and non-self peptidome by the class I Ag-processing machinery and its impact on Th-cell responses.

Authors:  Charles T Spencer; Srdjan M Dragovic; Stephanie B Conant; Jennifer J Gray; Mu Zheng; Parimal Samir; Xinnan Niu; Magdalini Moutaftsi; Luc Van Kaer; Alessandro Sette; Andrew J Link; Sebastian Joyce
Journal:  Eur J Immunol       Date:  2013-03-05       Impact factor: 5.532

9.  A crucial role for B and T lymphocyte attenuator in preventing the development of CD4+ T cell-mediated herpetic stromal keratitis.

Authors:  Likun Xia; Shengnan Zhang; Jiazi Zhou; Yan Li
Journal:  Mol Vis       Date:  2010-10-13       Impact factor: 2.367

10.  Non-mitogenic anti-CD3F(ab')2 monoclonal antibody: a novel approach to control herpetic stromal keratitis.

Authors:  Pranita P Sarangi; Bumseok Kim; Barry T Rouse
Journal:  Invest Ophthalmol Vis Sci       Date:  2008-08-08       Impact factor: 4.799
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