Literature DB >> 15060529

AMP kinase and malonyl-CoA: targets for therapy of the metabolic syndrome.

Neil Ruderman1, Marc Prentki.   

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Year:  2004        PMID: 15060529     DOI: 10.1038/nrd1344

Source DB:  PubMed          Journal:  Nat Rev Drug Discov        ISSN: 1474-1776            Impact factor:   84.694


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  133 in total

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Review 3.  Insulin resistance due to nutrient excess: is it a consequence of AMPK downregulation?

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Review 4.  Islet beta cell failure in type 2 diabetes.

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Review 5.  The metabolic syndrome and the heart--a considered opinion.

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8.  Leptinomimetic effects of the AMP kinase activator AICAR in leptin-resistant rats: prevention of diabetes and ectopic lipid deposition.

Authors:  X Yu; S McCorkle; M Wang; Y Lee; J Li; A K Saha; R H Unger; N B Ruderman
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9.  Inhibition of ABCA1 protein degradation promotes HDL cholesterol efflux capacity and RCT and reduces atherosclerosis in mice.

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10.  Adiponectin decreases C-reactive protein synthesis and secretion from endothelial cells: evidence for an adipose tissue-vascular loop.

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