Literature DB >> 1506041

Antifilarial activity of Centratherum anthelminticum seed extracts on Setaria cervi.

K C Singhal1, S Sharma, B K Mehta.   

Abstract

Effect of aqueous and alcoholic extract of C. anthelminticum was studied on the spontaneous movements of the whole worm and nerve-muscle preparation of S. cervi. Ethylacetate, acetone and methanol extract showed similar effect, of causing inhibition of spontaneous motility of the nerve-muscle preparation of S. cervi characterized by decreased amplitude and frequency of contractions. The inhibitory effect on the motility was reversible. Further, the extracts did not involve the blockade of cholinergic receptors as evidenced by the presence of unaltered stimulant response of acetylcholine in the presence of drug in bathing fluid.

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Year:  1992        PMID： 1506041

Source DB:  PubMed          Journal:  Indian J Exp Biol        ISSN： 0019-5189            Impact factor:   0.818


  8 in total

1.  In vitro screening of medicinal plant extracts for macrofilaricidal activity.

Authors:  Mathew Nisha; M Kalyanasundaram; K P Paily; P Vanamail; K Balaraman
Journal:  Parasitol Res       Date:  2006-09-30       Impact factor: 2.289

2.  Induction of apoptosis in human breast cancer cells via caspase pathway by vernodalin isolated from Centratherum anthelminticum (L.) seeds.

Authors:  Chung Yeng Looi; Aditya Arya; Foo Kit Cheah; Bushra Muharram; Kok Hoong Leong; Khalit Mohamad; Won Fen Wong; Nitika Rai; Mohd Rais Mustafa
Journal:  PLoS One       Date:  2013-02-20       Impact factor: 3.240

3.  Antioxidant potential of bitter cumin (Centratherum anthelminticum (L.) Kuntze) seeds in in vitro models.

Authors:  V Ani; Kamatham A Naidu
Journal:  BMC Complement Altern Med       Date:  2011-05-20       Impact factor: 3.659

4.  Chloroform Fraction of Centratherum anthelminticum (L.) Seed Inhibits Tumor Necrosis Factor Alpha and Exhibits Pleotropic Bioactivities: Inhibitory Role in Human Tumor Cells.

Authors:  Aditya Arya; Mouna Achoui; Shiau-Chuen Cheah; Siddig Ibrahim Abdelwahab; Putri Narrima; Syam Mohan; Mohd Rais Mustafa; Mustafa Ali Mohd
Journal:  Evid Based Complement Alternat Med       Date:  2012-02-28       Impact factor: 2.629

5.  Induction of apoptosis in melanoma A375 cells by a chloroform fraction of Centratherum anthelminticum (L.) seeds involves NF-kappaB, p53 and Bcl-2-controlled mitochondrial signaling pathways.

Authors:  Chung Yeng Looi; Bushra Moharram; Mohammadjavad Paydar; Yi Li Wong; Kok Hoong Leong; Khalit Mohamad; Aditya Arya; Won Fen Wong; Mohd Rais Mustafa
Journal:  BMC Complement Altern Med       Date:  2013-07-10       Impact factor: 3.659

6.  Vernodalol mediates antitumor effects in acute promyelocytic leukemia cells.

Authors:  Wenjun Wu; Xiaoyan Han; Cai Wu; Guoqing Wei; Gaofeng Zheng; Yi Li; Yang Yang; Li Yang; Donghua He; Yi Zhao; Zhen Cai
Journal:  Oncol Lett       Date:  2017-12-07       Impact factor: 2.967

7.  Extracts of Euphorbia hirta Linn. (Euphorbiaceae) and Rauvolfia vomitoria Afzel (Apocynaceae) demonstrate activities against Onchocerca volvulus microfilariae in vitro.

Authors:  Simon K Attah; Patrick F Ayeh-Kumi; Archibald A Sittie; Isaac V Oppong; Alexander K Nyarko
Journal:  BMC Complement Altern Med       Date:  2013-03-18       Impact factor: 3.659

8.  Forkhead Box Transcription Factor (FOXO3a) mediates the cytotoxic effect of vernodalin in vitro and inhibits the breast tumor growth in vivo.

Authors:  Suresh Kumar Ananda Sadagopan; Nooshin Mohebali; Chung Yeng Looi; Mohadeseh Hasanpourghadi; Ashok Kumar Pandurangan; Aditya Arya; Hamed Karimian; Mohd Rais Mustafa
Journal:  J Exp Clin Cancer Res       Date:  2015-12-08
  8 in total

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