Literature DB >> 1505991

Clustering of C2-H2 zinc finger motif sequences within telomeric and fragile site regions of human chromosomes.

P Lichter1, P Bray, T Ried, I B Dawid, D C Ward.   

Abstract

Ninety-three phage clones identified by hybridization with a C2-H2 zinc finger sequence probe have been grouped into 23 genetic loci. Partial sequencing verified that each locus belonged to the zinc finger family. Oligonucleotide primer pairs were developed from these sequences to serve as STS markers for these loci. One or more clones from each locus was mapped onto human metaphase chromosomes by fluorescence in situ hybridization. Several loci map to identical chromosomal regions, indicating the possible presence of multigene clusters. Zinc finger loci were found to reside predominantly either in telomeric regions or in chromosomal bands known to exhibit chromosome fragility. Chromosome 19 carries a disproportionate fraction (10 of 23) of the mapped zinc finger loci.

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Year:  1992        PMID： 1505991     DOI： 10.1016/0888-7543(92)90013-i

Source DB:  PubMed          Journal:  Genomics        ISSN： 0888-7543            Impact factor:   5.736


  15 in total

1.  Localisation of a gene causing endocrine neoplasia to a 4 cM region on chromosome 1p35-p36.

Authors:  C Williamson; A A Pannett; J T Pang; C Wooding; M McCarthy; M N Sheppard; J Monson; R N Clayton; R V Thakker
Journal:  J Med Genet       Date:  1997-08       Impact factor: 6.318

2.  The enigma of common fragile sites.

Authors:  I Simonic; G S Gericke
Journal:  Hum Genet       Date:  1996-04       Impact factor: 4.132

3.  Localization of zinc finger Mok2 gene to mouse chromosome 6, a new region of homology with human chromosome 19.

Authors:  V Arranz; M Kress; M Ernoult-Lange
Journal:  Mamm Genome       Date:  1996-01       Impact factor: 2.957

4.  The human homolog of a mouse-imprinted gene, Peg3, maps to a zinc finger gene-rich region of human chromosome 19q13.4.

Authors:  J Kim; L Ashworth; E Branscomb; L Stubbs
Journal:  Genome Res       Date:  1997-05       Impact factor: 9.043

5.  Emergence of the ZNF91 Krüppel-associated box-containing zinc finger gene family in the last common ancestor of anthropoidea.

Authors:  E J Bellefroid; J C Marine; A G Matera; C Bourguignon; T Desai; K C Healy; P Bray-Ward; J A Martial; J N Ihle; D C Ward
Journal:  Proc Natl Acad Sci U S A       Date:  1995-11-07       Impact factor: 11.205

6.  Clustered organization and conservation of the Xiphophorus maculatus D locus, which includes two distinct gene sequences.

Authors:  I Nanda; S Weis; D Förnzler; J Altschmied; M Schartl; M Schmid
Journal:  Chromosoma       Date:  1996-10       Impact factor: 4.316

7.  A multifaceted FISH approach to study endogenous RNAs and DNAs in native nuclear and cell structures.

Authors:  Meg Byron; Lisa L Hall; Jeanne B Lawrence
Journal:  Curr Protoc Hum Genet       Date:  2013-01

8.  Duplicated KOX zinc finger gene clusters flank the centromere of human chromosome 10: evidence for a pericentric inversion during primate evolution.

Authors:  A Tunnacliffe; L Liu; J K Moore; M A Leversha; M S Jackson; L Papi; M A Ferguson-Smith; H J Thiesen; B A Ponder
Journal:  Nucleic Acids Res       Date:  1993-03-25       Impact factor: 16.971

9.  Construction of an approximately 700-kb transcript map around the familial Mediterranean fever locus on human chromosome 16p13.3.

Authors:  M Centola; X Chen; R Sood; Z Deng; I Aksentijevich; T Blake; D O Ricke; X Chen; G Wood; N Zaks; N Richards; D Krizman; E Mansfield; S Apostolou; J Liu; N Shafran; A Vedula; M Hamon; A Cercek; T Kahan; D Gumucio; D F Callen; R I Richards; R K Moyzis; N A Doggett; F S Collins; P P Liu; N Fischel-Ghodsian; D L Kastner
Journal:  Genome Res       Date:  1998-11       Impact factor: 9.043

10.  Human and mouse Krüppel-like (MOK2) orthologue genes encode two different zinc finger proteins.

Authors:  M Ernoult-Lange; V Arranz; M Le Coniat; R Berger; M Kress
Journal:  J Mol Evol       Date:  1995-12       Impact factor: 2.395
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