Literature DB >> 15058557

The use of phosphatidylcholine for correction of localized fat deposits.

Patrícia Guedes Rittes1.   

Abstract

Subjects with localized fat deposits commonly receive suction lipectomy as a cosmetic procedure. A new office procedure for correction of those superficial fat deposits was applied in 50 patients by injection of phosphatidylcholine. The method itself consists of using a 3OG1/2 insulin needle to inject about 5 ml (250 mg/5 ml) of phosphatidylcholine into the fat, distributing it evenly in an 80 cm2 area. Pre- and posttreatment photographs were taken for technical planning and analysis of the results over the long term. A clear improvement occurred in all, with a marked reduction of the fat deposits without recurrence over a 2-year follow-up period and no weight gain. The injection of phosphatidylcholine into the fat deposits is a simple office procedure that can sometimes postpone or even replace surgery and liposuction.

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Year:  2003        PMID: 15058557     DOI: 10.1007/s00266-003-3033-y

Source DB:  PubMed          Journal:  Aesthetic Plast Surg        ISSN: 0364-216X            Impact factor:   2.326


  14 in total

1.  [Injection lipolysis].

Authors:  K Hoffmann
Journal:  Hautarzt       Date:  2010-10       Impact factor: 0.751

2.  The effect of phosphatidylcholine and deoxycholate compound injections to the localized adipose tissue: an experimental study with a murine model.

Authors:  Yongjoon Noh; Chan-Yeong Heo
Journal:  Arch Plast Surg       Date:  2012-09-12

3.  Phosphatidylcholine induces apoptosis of 3T3-L1 adipocytes.

Authors:  Hailan Li; Jong-Hyuk Lee; Su Yeon Kim; Hye-Young Yun; Kwang Jin Baek; Nyoun Soo Kwon; Yoosik Yoon; Ji Hoon Jeong; Dong-Seok Kim
Journal:  J Biomed Sci       Date:  2011-12-07       Impact factor: 8.410

4.  Results from a pooled analysis of two European, randomized, placebo-controlled, phase 3 studies of ATX-101 for the pharmacologic reduction of excess submental fat.

Authors:  James McDiarmid; Jesus Benito Ruiz; Daniel Lee; Susanne Lippert; Claudia Hartisch; Blanka Havlickova
Journal:  Aesthetic Plast Surg       Date:  2014-07-02       Impact factor: 2.326

5.  Selective effect of phosphatidylcholine on the lysis of adipocytes.

Authors:  Ji-Young Kim; Min-Seo Kwon; Junghyun Son; Sang-Wook Kang; Youngsup Song
Journal:  PLoS One       Date:  2017-05-02       Impact factor: 3.240

6.  Evaluation of Safe and Effectiveness of an Injectable Solution Acid Deoxycholic Based for Reduction of Localized Adiposities.

Authors:  Roberto Amore; Domenico Amuso; Vincenza Leonardi; Francesco Leva; Andrea Carnovale Sibaud; Antonio Guida; Ezio Costa; Ferdinando Terranova; Vincenzo Amodeo; Konstantinos Gkritzalas
Journal:  Plast Reconstr Surg Glob Open       Date:  2018-06-11

7.  Phosphatidylcholine causes adipocyte-specific lipolysis and apoptosis in adipose and muscle tissues.

Authors:  Tae Woo Jung; Taekwang Park; Jinwoo Park; Uiseok Kim; Hyun Dong Je; Hyeong-Dong Kim; Seong-Wan Cho; A M Abd El-Aty; Jin-Ho Song; Hyoung-Chun Kim; Yong Kyoo Shin; Ji Hoon Jeong
Journal:  PLoS One       Date:  2019-04-08       Impact factor: 3.240

8.  Intracutaneous Delivery of Gelatins Reduces Fat Accumulation in Subcutaneous Adipose Tissue.

Authors:  Sung-Min An; Min Jae Kim; Keum-Yong Seong; Jea Sic Jeong; Hyeon-Gu Kang; So Young Kim; Da Som Kim; Da Hee Kang; Seung Yun Yang; Beum-Soo An
Journal:  Toxicol Res       Date:  2019-10-15

9.  Reduction of unwanted submental fat with ATX-101 (deoxycholic acid), an adipocytolytic injectable treatment: results from a phase III, randomized, placebo-controlled study.

Authors:  B Rzany; T Griffiths; P Walker; S Lippert; J McDiarmid; B Havlickova
Journal:  Br J Dermatol       Date:  2014-02       Impact factor: 9.302

10.  Intralipotherapy, the State of the Art.

Authors:  Roberto Amore; Hernán Pinto; Kostas Gritzalas; Carlota Hernández; Katarzyna Skwara-Guzikowska; Domenico Amuso; Vincenza Leonardi
Journal:  Plast Reconstr Surg Glob Open       Date:  2016-10-27
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