Literature DB >> 15056354

Toxicity of concentrated sodium hypochlorite used as an endodontic irrigant.

C R Gernhardt1, K Eppendorf, A Kozlowski, M Brandt.   

Abstract

AIM: To present a clinical case that illustrates the toxicity of concentrated sodium hypochlorite (NaOCl) on vital tissues.
SUMMARY: The severe clinical consequences of extruding concentrated NaOCl into the periradicular tissues during root canal irrigation are described. After diagnosis of external resorption in tooth 34, endodontic treatment was initiated. Following irrigation with a concentrated NaOCl solution, a rapidly developing swelling and haematoma were visible. During the next few days, an extensive bruise and local necrosis of the oral mucosa developed. After healing of the involved tissues, the canal was prepared and obturated. At this time, no clinical symptoms remained. KEY LEARNING POINTS: * The use of concentrated NaOCl as a root canal irrigant might cause severe clinical problems when extruded into vital tissues. * The present report confirms the known toxicity of NaOCl to soft tissues following inadvertent extrusion. * To avoid extrusion, it is always prudent to confirm the length and integrity of the root canal system before irrigating with concentrated solutions.

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Year:  2004        PMID: 15056354     DOI: 10.1111/j.0143-2885.2004.00804.x

Source DB:  PubMed          Journal:  Int Endod J        ISSN: 0143-2885            Impact factor:   5.264


  33 in total

Review 1.  Anatomy of sodium hypochlorite accidents involving facial ecchymosis - a review.

Authors:  Wan-chun Zhu; Jacqueline Gyamfi; Li-na Niu; G John Schoeffel; Si-ying Liu; Filippo Santarcangelo; Sara Khan; Kelvin C-Y Tay; David H Pashley; Franklin R Tay
Journal:  J Dent       Date:  2013-08-28       Impact factor: 4.379

2.  Comparison of the antibacterial efficiency of neem leaf extracts, grape seed extracts and 3% sodium hypochlorite against E. feacalis - An in vitro study.

Authors:  Wasudeo Namdeo Ghonmode; Omkar D Balsaraf; Varsha H Tambe; K P Saujanya; Ashishkumar K Patil; Deepak D Kakde
Journal:  J Int Oral Health       Date:  2013-12-26

3.  Anti bacterial Effectiveness of Electro- Chemically Activated (ECA) Water as a Root Canal Irrigant- An In-vitro Comparative Study.

Authors:  S Lata; Soumya Kanta Mohanty; Prasanti Kumari Pradhan; Gaurav Patri; Sachidananda Prasad Sinha; Pratik Agrawal
Journal:  J Clin Diagn Res       Date:  2016-10-01

4.  Radiographic examination of apical extrusion of root canal irrigants during cavitation induced by Er,Cr:YSGG laser irradiation: an in vivo study.

Authors:  Harry Huiz Peeters; Latief Mooduto
Journal:  Clin Oral Investig       Date:  2012-12-28       Impact factor: 3.573

5.  Effects of photodynamic therapy, 2 % chlorhexidine, triantibiotic mixture, propolis and ozone on root canals experimentally infected with Enterococcus faecalis: an in vitro study.

Authors:  Fabio Camacho-Alonso; P Salmerón-Lozano; Y Martínez-Beneyto
Journal:  Odontology       Date:  2016-10-22       Impact factor: 2.634

6.  Comparison of ozone gas and sodium hypochlorite/chlorhexidine two-visit disinfection protocols in treating apical periodontitis: a randomized controlled clinical trial.

Authors:  Stefan Kist; Maximilian Kollmuss; Jette Jung; Sören Schubert; Reinhard Hickel; Karin Christine Huth
Journal:  Clin Oral Investig       Date:  2016-05-12       Impact factor: 3.573

7.  Effect of 5% Chlorine Dioxide Irrigant on Micro Push Out Bond Strength of Resin Sealer to Radicular Dentin: An In Vitro Study.

Authors:  Rejitha R Kamalasanan; Swapna V Devarasanahalli; Ranjini M Aswathanarayana; K Rashmi; Yashwanth Gowda; Roopa R Nadig
Journal:  J Clin Diagn Res       Date:  2017-05-01

8.  Comparison of sodium hypochlorite extrusion by five irrigation systems using an artificial root socket model and a quantitative chemical method.

Authors:  Adham A Azim; Hacer Aksel; M Margaret Jefferson; George T-J Huang
Journal:  Clin Oral Investig       Date:  2017-07-26       Impact factor: 3.573

9.  ToxiM: A Toxicity Prediction Tool for Small Molecules Developed Using Machine Learning and Chemoinformatics Approaches.

Authors:  Ashok K Sharma; Gopal N Srivastava; Ankita Roy; Vineet K Sharma
Journal:  Front Pharmacol       Date:  2017-11-30       Impact factor: 5.810

10.  Subcutaneous emphysema during root canal therapy: endodontic accident by sodium hypoclorite.

Authors:  Gianluca Tenore; Gaspare Palaia; Chiara Ciolfi; Mohamed Mohsen; Andrea Battisti; Umberto Romeo
Journal:  Ann Stomatol (Roma)       Date:  2018-03-08
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