Literature DB >> 15056142

From road rash to top allergen in a flash: bacitracin.

Sharon E Jacob1, William D James.   

Abstract

BACKGROUND: Bacitracin is an antibiotic that is produced by Bacillus subtilis, which is used in several types of consumer products, including cosmetics and ophthalmic and cutaneous ointments.
OBJECTIVE: To call attention to the rising allergic contact dermatitis associated with bacitracin.
RESULTS: Mass usage has resulted in an increasing number of clinically relevant allergic contact dermatitis reactions and near fatal anaphylaxis. The North American Contact Dermatitis Group has recorded its emergence as a leading allergen and continues to monitor the ever-growing allergic reaction rates.
CONCLUSION: The clinical impact, scientific evidence, and need for medical cost containment all advocate the discontinuation of routine usage of bacitracin in clean surgical wounds.

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Year:  2004        PMID: 15056142     DOI: 10.1111/j.1524-4725.2004.30168.x

Source DB:  PubMed          Journal:  Dermatol Surg        ISSN: 1076-0512            Impact factor:   3.398


  5 in total

1.  Knowledge of Surgery-Related Allergic Contact Dermatitis among Florida Dermatological Surgeons: A Pilot Study.

Authors:  Panta Rouhani; Robert S Kirsner; Antoine Amado; Lora E Fleming; Keyvan Nouri; Sharon E Jacob
Journal:  J Clin Aesthet Dermatol       Date:  2009-11

2.  Opposing effects of bacitracin on human papillomavirus type 16 infection: enhancement of binding and entry and inhibition of endosomal penetration.

Authors:  Samuel K Campos; Janice A Chapman; Martin J Deymier; Matthew P Bronnimann; Michelle A Ozbun
Journal:  J Virol       Date:  2012-02-15       Impact factor: 5.103

3.  Allergic Contact Dermatitis: Patch Testing Beyond the TRUE Test.

Authors:  Jenny L Nelson; Christen M Mowad
Journal:  J Clin Aesthet Dermatol       Date:  2010-10

4.  Comparison of a Novel Silicone Gel Wound Dressing vs Bacitracin After Follicular Unit Extraction Hair Transplantation.

Authors:  Isaac B James; David M Turer; Barry E DiBernardo
Journal:  Aesthet Surg J Open Forum       Date:  2021-12-13

5.  Anaphylaxis to topically applied sodium fusidate.

Authors:  Mi-Ran Park; Do-Soo Kim; Jihyun Kim; Kangmo Ahn
Journal:  Allergy Asthma Immunol Res       Date:  2012-11-02       Impact factor: 5.764

  5 in total

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